ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	132/888	423/7206	1.71890734118e-26
ko05033	Nicotine addiction	39/888	56/7206	1.99393792541e-23
ko04724	Glutamatergic synapse	67/888	152/7206	5.59354618954e-23
ko04728	Dopaminergic synapse	68/888	185/7206	4.36113076339e-18
ko04721	Synaptic vesicle cycle	41/888	80/7206	2.01013148744e-17
ko05032	Morphine addiction	48/888	110/7206	1.4916331754e-16
ko04713	Circadian entrainment	53/888	136/7206	1.3718182091e-15
ko04024	cAMP signaling pathway	81/888	279/7206	2.21892388711e-14
ko04727	GABAergic synapse	45/888	110/7206	2.48179771157e-14
ko04360	Axon guidance	68/888	233/7206	3.15306430401e-12
ko04723	Retrograde endocannabinoid signaling	56/888	175/7206	3.52847590001e-12
ko04725	Cholinergic synapse	50/888	160/7206	1.37223060924e-10
ko04744	Phototransduction	19/888	36/7206	4.84069445471e-09
ko04911	Insulin secretion	38/888	117/7206	7.10513839291e-09
ko04726	Serotonergic synapse	42/888	137/7206	8.01452521662e-09
ko05031	Amphetamine addiction	31/888	91/7206	5.05162148997e-08
ko05203	Viral carcinogenesis	9/888	277/7206	1.13201395168e-07
ko04261	Adrenergic signaling in cardiomyocytes	52/888	205/7206	2.13028914336e-07
ko05030	Cocaine addiction	26/888	73/7206	2.22182021199e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/888	74/7206	3.03103737464e-07
ko04742	Taste transduction	23/888	61/7206	3.41011908832e-07
ko04720	Long-term potentiation	31/888	99/7206	4.38458352807e-07
ko04514	Cell adhesion molecules (CAMs)	36/888	130/7206	2.12666190589e-06
ko03040	Spliceosome	2/888	145/7206	2.24749662795e-06
ko04060	Cytokine-cytokine receptor interaction	5/888	191/7206	2.99997591014e-06
ko04970	Salivary secretion	28/888	95/7206	9.38175071073e-06
ko04020	Calcium signaling pathway	57/888	265/7206	2.21756362462e-05
ko03013	RNA transport	5/888	166/7206	3.63100660758e-05
ko04921	Oxytocin signaling pathway	47/888	209/7206	3.78977613244e-05
ko04966	Collecting duct acid secretion	11/888	26/7206	0.000124463650195
ko04120	Ubiquitin mediated proteolysis	4/888	138/7206	0.000190015402901
ko04146	Peroxisome	1/888	89/7206	0.000235679009814
ko04022	cGMP-PKG signaling pathway	45/888	216/7206	0.000311380777357
ko05168	Herpes simplex infection	8/888	182/7206	0.000351072085305
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/888	182/7206	0.000351072085305
ko04141	Protein processing in endoplasmic reticulum	8/888	184/7206	0.00036114845498
ko04730	Long-term depression	21/888	78/7206	0.000380796332213
ko05322	Systemic lupus erythematosus	6/888	151/7206	0.000631105871921
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/888	14/7206	0.000659561745805
ko03008	Ribosome biogenesis in eukaryotes	1/888	79/7206	0.000774253981579
ko05162	Measles	4/888	120/7206	0.00107329336607
ko04972	Pancreatic secretion	26/888	111/7206	0.00110522097999
ko04010	MAPK signaling pathway	59/888	321/7206	0.00125883491028
ko01200	Carbon metabolism	5/888	128/7206	0.00161424514749
ko04964	Proximal tubule bicarbonate reclamation	10/888	29/7206	0.00169386926673
ko05164	Influenza A	8/888	167/7206	0.00173404503088
ko04971	Gastric acid secretion	23/888	98/7206	0.00175863743775
ko00515	Mannose type O-glycan biosynthesis	9/888	25/7206	0.00204205751409
ko03018	RNA degradation	2/888	84/7206	0.00225381567923
ko04540	Gap junction	28/888	128/7206	0.0024548388041
ko04064	NF-kappa B signaling pathway	3/888	96/7206	0.00268178280774
ko04621	NOD-like receptor signaling pathway	8/888	157/7206	0.00306670911068
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/888	79/7206	0.00314269884924
ko05110	Vibrio cholerae infection	16/888	63/7206	0.00351956832302
ko04014	Ras signaling pathway	50/888	279/7206	0.00522986297105
ko00330	Arginine and proline metabolism	1/888	61/7206	0.0053543890254
ko05205	Proteoglycans in cancer	19/888	271/7206	0.00601962714359
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/888	15/7206	0.00642943156125
ko05169	Epstein-Barr virus infection	13/888	206/7206	0.00677923083711
ko05146	Amoebiasis	4/888	99/7206	0.00815865220367
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/888	92/7206	0.00979819890515
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	8/888	26/7206	0.0104924649163
ko00280	Valine, leucine and isoleucine degradation	1/888	54/7206	0.0116667987714
ko00480	Glutathione metabolism	1/888	55/7206	0.0118215793897
ko04924	Renin secretion	19/888	86/7206	0.0118430873863
ko04260	Cardiac muscle contraction	21/888	98/7206	0.0120296658664
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/888	59/7206	0.0146856502322
ko04391	Hippo signaling pathway - fly	19/888	90/7206	0.0151554901549
ko00380	Tryptophan metabolism	1/888	50/7206	0.0172239820583
ko03460	Fanconi anemia pathway	1/888	51/7206	0.0172411641457
ko00590	Arachidonic acid metabolism	1/888	52/7206	0.0175644457879
ko05166	HTLV-I infection	23/888	292/7206	0.0177506390627
ko04071	Sphingolipid signaling pathway	30/888	162/7206	0.0209140486219
ko05140	Leishmaniasis	3/888	75/7206	0.0214075169455
ko01524	Platinum drug resistance	3/888	76/7206	0.0214596808688
ko04612	Antigen processing and presentation	3/888	77/7206	0.0217542717487
ko04630	Jak-STAT signaling pathway	8/888	132/7206	0.0229739024119
ko04740	Olfactory transduction	17/888	80/7206	0.0241122869862
ko00270	Cysteine and methionine metabolism	1/888	47/7206	0.0253041512656
ko04211	Longevity regulating pathway	7/888	123/7206	0.0255173713761
ko00240	Pyrimidine metabolism	6/888	110/7206	0.0270525405861
ko04611	Platelet activation	11/888	163/7206	0.029162705085
ko04140	Autophagy - animal	11/888	164/7206	0.0294900668384
ko00310	Lysine degradation	3/888	73/7206	0.0301156006507
ko05034	Alcoholism	40/888	238/7206	0.0353739721451
ko04072	Phospholipase D signaling pathway	34/888	197/7206	0.0367276093892
ko03022	Basal transcription factors	1/888	44/7206	0.0371772605307
ko05144	Malaria	1/888	45/7206	0.0376393060229
ko00071	Fatty acid degradation	1/888	45/7206	0.0376393060229
ko04138	Autophagy - yeast	4/888	81/7206	0.0404400687463
ko04110	Cell cycle	10/888	145/7206	0.0413737138991
ko04070	Phosphatidylinositol signaling system	21/888	112/7206	0.0424167797209
ko04915	Estrogen signaling pathway	24/888	131/7206	0.0432119854099
ko04745	Phototransduction - fly	9/888	38/7206	0.0443567827298
ko05016	Huntington's disease	17/888	215/7206	0.0451350854993
ko04925	Aldosterone synthesis and secretion	20/888	105/7206	0.0497653399512