ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	64/764	152/7206	2.60733777491e-24
ko05033	Nicotine addiction	36/764	56/7206	3.80060596795e-22
ko04080	Neuroactive ligand-receptor interaction	112/764	423/7206	1.95425299339e-21
ko04728	Dopaminergic synapse	59/764	185/7206	1.20352493552e-15
ko04721	Synaptic vesicle cycle	36/764	80/7206	2.8732239309e-15
ko04727	GABAergic synapse	41/764	110/7206	8.80270828883e-14
ko05032	Morphine addiction	41/764	110/7206	8.80270828883e-14
ko04713	Circadian entrainment	44/764	136/7206	3.32489856013e-12
ko04725	Cholinergic synapse	48/764	160/7206	7.5175536141e-12
ko04723	Retrograde endocannabinoid signaling	50/764	175/7206	2.01966014082e-11
ko04024	cAMP signaling pathway	64/764	279/7206	1.07304423511e-09
ko04911	Insulin secretion	34/764	117/7206	2.23334481732e-08
ko04360	Axon guidance	53/764	233/7206	5.12010602458e-08
ko05031	Amphetamine addiction	28/764	91/7206	1.0365659803e-07
ko04514	Cell adhesion molecules (CAMs)	35/764	130/7206	1.15782616725e-07
ko04261	Adrenergic signaling in cardiomyocytes	47/764	205/7206	2.06805617474e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/764	74/7206	2.84357429094e-07
ko05030	Cocaine addiction	23/764	73/7206	8.98809980661e-07
ko04726	Serotonergic synapse	34/764	137/7206	1.58120093473e-06
ko03040	Spliceosome	1/764	145/7206	3.33001072749e-06
ko05203	Viral carcinogenesis	9/764	277/7206	5.92147940154e-06
ko04720	Long-term potentiation	26/764	99/7206	8.11604966942e-06
ko04060	Cytokine-cytokine receptor interaction	4/764	191/7206	1.18972281107e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/764	14/7206	2.58153955813e-05
ko04742	Taste transduction	18/764	61/7206	3.74511884691e-05
ko04120	Ubiquitin mediated proteolysis	2/764	138/7206	6.05091244435e-05
ko04921	Oxytocin signaling pathway	41/764	209/7206	8.37900747127e-05
ko05164	Influenza A	4/764	167/7206	0.000102245369505
ko05168	Herpes simplex infection	5/764	182/7206	0.000121009725237
ko04010	MAPK signaling pathway	56/764	321/7206	0.000130475142658
ko04744	Phototransduction	12/764	36/7206	0.000208124359812
ko04020	Calcium signaling pathway	48/764	265/7206	0.000215276744736
ko04970	Salivary secretion	22/764	95/7206	0.0003182969753
ko03013	RNA transport	5/764	166/7206	0.000472969532267
ko04730	Long-term depression	19/764	78/7206	0.000534048823991
ko04966	Collecting duct acid secretion	9/764	26/7206	0.0009529587209
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/764	79/7206	0.00138948435722
ko05169	Epstein-Barr virus infection	9/764	206/7206	0.0017747111203
ko03008	Ribosome biogenesis in eukaryotes	1/764	79/7206	0.00267651253015
ko04141	Protein processing in endoplasmic reticulum	8/764	184/7206	0.0033237738073
ko04621	NOD-like receptor signaling pathway	6/764	157/7206	0.00351832305263
ko04971	Gastric acid secretion	20/764	98/7206	0.00413857466142
ko00240	Pyrimidine metabolism	3/764	110/7206	0.00427792633887
ko04972	Pancreatic secretion	22/764	111/7206	0.00441359002244
ko05205	Proteoglycans in cancer	15/764	271/7206	0.00459632048162
ko05322	Systemic lupus erythematosus	6/764	151/7206	0.00468135617628
ko04146	Peroxisome	2/764	89/7206	0.00508016214457
ko04214	Apoptosis - fly	1/764	72/7206	0.00589668545681
ko00310	Lysine degradation	1/764	73/7206	0.00609507836816
ko05162	Measles	4/764	120/7206	0.00637613692982
ko04022	cGMP-PKG signaling pathway	36/764	216/7206	0.00663153646168
ko04064	NF-kappa B signaling pathway	3/764	96/7206	0.0115587604586
ko00561	Glycerolipid metabolism	1/764	63/7206	0.0124476551644
ko04640	Hematopoietic cell lineage	1/764	64/7206	0.0126269376788
ko04540	Gap junction	23/764	128/7206	0.0126501677826
ko04014	Ras signaling pathway	43/764	279/7206	0.0126717279896
ko04072	Phospholipase D signaling pathway	32/764	197/7206	0.0132212831019
ko04915	Estrogen signaling pathway	23/764	131/7206	0.0140644221093
ko04612	Antigen processing and presentation	2/764	77/7206	0.0149495292313
ko04391	Hippo signaling pathway - fly	17/764	90/7206	0.015232504893
ko05161	Hepatitis B	9/764	173/7206	0.0169737629296
ko00330	Arginine and proline metabolism	1/764	61/7206	0.0189037795383
ko04260	Cardiac muscle contraction	18/764	98/7206	0.0191773804224
ko04110	Cell cycle	7/764	145/7206	0.0197915446397
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/764	182/7206	0.0201609443142
ko05110	Vibrio cholerae infection	13/764	63/7206	0.0205211099722
ko05140	Leishmaniasis	2/764	75/7206	0.0216772877989
ko00480	Glutathione metabolism	1/764	55/7206	0.0266581692937
ko01200	Carbon metabolism	6/764	128/7206	0.0284193936241
ko00512	Mucin type O-glycan biosynthesis	7/764	29/7206	0.0285374327284
ko04964	Proximal tubule bicarbonate reclamation	7/764	29/7206	0.0285374327284
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/764	59/7206	0.0296799760827
ko05146	Amoebiasis	4/764	99/7206	0.0311759192292
ko05166	HTLV-I infection	20/764	292/7206	0.0324736513538
ko04626	Plant-pathogen interaction	5/764	18/7206	0.0350735446517
ko00590	Arachidonic acid metabolism	1/764	52/7206	0.0392331467449
ko05120	Epithelial cell signaling in Helicobacter pylori infection	16/764	92/7206	0.0402300427578
ko00280	Valine, leucine and isoleucine degradation	1/764	54/7206	0.0412180046547
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/764	8/7206	0.0442322114487
ko04137	Mitophagy - animal	3/764	82/7206	0.0444760983635
ko04630	Jak-STAT signaling pathway	7/764	132/7206	0.0451443415451