ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 18/145 134/7206 1.27528177497e-10 ko04060 Cytokine-cytokine receptor interaction 21/145 191/7206 1.54989524817e-10 ko04621 NOD-like receptor signaling pathway 18/145 157/7206 1.78930389046e-09 ko04630 Jak-STAT signaling pathway 14/145 132/7206 3.40310624112e-07 ko04064 NF-kappa B signaling pathway 12/145 96/7206 4.09436675957e-07 ko04650 Natural killer cell mediated cytotoxicity 12/145 97/7206 4.5925671145e-07 ko04620 Toll-like receptor signaling pathway 11/145 100/7206 4.57679380168e-06 ko05152 Tuberculosis 15/145 187/7206 4.61105090947e-06 ko05150 Staphylococcus aureus infection 7/145 36/7206 5.91720848406e-06 ko04660 T cell receptor signaling pathway 12/145 124/7206 6.44262340531e-06 ko04610 Complement and coagulation cascades 9/145 79/7206 2.62031787591e-05 ko04662 B cell receptor signaling pathway 9/145 88/7206 6.23866140831e-05 ko05321 Inflammatory bowel disease (IBD) 7/145 56/7206 0.000117465088711 ko05164 Influenza A 12/145 167/7206 0.00012643616816 ko04668 TNF signaling pathway 10/145 120/7206 0.000139988559187 ko04623 Cytosolic DNA-sensing pathway 6/145 41/7206 0.000150567688986 ko05144 Malaria 6/145 45/7206 0.000255297019478 ko05340 Primary immunodeficiency 5/145 30/7206 0.0002924006568 ko05323 Rheumatoid arthritis 8/145 89/7206 0.00039547577943 ko04611 Platelet activation 11/145 163/7206 0.000419117460458 ko05162 Measles 9/145 120/7206 0.000662134275285 ko05140 Leishmaniasis 7/145 75/7206 0.000731411187539 ko05132 Salmonella infection 8/145 98/7206 0.000756977400775 ko04217 Necroptosis 11/145 178/7206 0.000879117315345 ko05142 Chagas disease (American trypanosomiasis) 9/145 130/7206 0.0011763625993 ko05131 Shigellosis 7/145 82/7206 0.00124644855581 ko05133 Pertussis 7/145 87/7206 0.00176260060189 ko05161 Hepatitis B 10/145 173/7206 0.00247639224257 ko04666 Fc gamma R-mediated phagocytosis 8/145 122/7206 0.00309226698334 ko04210 Apoptosis 10/145 180/7206 0.0033026946502 ko04932 Non-alcoholic fatty liver disease (NAFLD) 10/145 182/7206 0.00357527390352 ko05134 Legionellosis 6/145 74/7206 0.00360366953099 ko05145 Toxoplasmosis 8/145 126/7206 0.00377130403003 ko04664 Fc epsilon RI signaling pathway 6/145 77/7206 0.00439120456437 ko04659 Th17 cell differentiation 7/145 106/7206 0.00536041410953 ko04062 Chemokine signaling pathway 10/145 201/7206 0.0071578599139 ko04622 RIG-I-like receptor signaling pathway 5/145 62/7206 0.00793854838433 ko05168 Herpes simplex infection 9/145 182/7206 0.0109528325886 ko04142 Lysosome 8/145 151/7206 0.0109689006063 ko04670 Leukocyte transendothelial migration 8/145 151/7206 0.0109689006063 ko04658 Th1 and Th2 cell differentiation 6/145 96/7206 0.0125964865052 ko04015 Rap1 signaling pathway 12/145 278/7206 0.013166044588 ko05167 Kaposi's sarcoma-associated herpesvirus infection 9/145 191/7206 0.0146758052469 ko04145 Phagosome 8/145 162/7206 0.0162352501262 ko05166 HTLV-I infection 12/145 292/7206 0.016733028263 ko05130 Pathogenic Escherichia coli infection 5/145 77/7206 0.019095771903 ko05418 Fluid shear stress and atherosclerosis 8/145 173/7206 0.0231302644905 ko05212 Pancreatic cancer 5/145 83/7206 0.025521293046 ko04657 IL-17 signaling pathway 5/145 87/7206 0.0304931903163 ko05160 Hepatitis C 7/145 153/7206 0.0343655254839 ko05221 Acute myeloid leukemia 4/145 63/7206 0.037542880264 ko04640 Hematopoietic cell lineage 4/145 64/7206 0.0394417392402 ko00660 C5-Branched dibasic acid metabolism 1/145 2/7206 0.0398420777817 ko04810 Regulation of actin cytoskeleton 10/145 264/7206 0.0440670914076 ko04071 Sphingolipid signaling pathway 7/145 162/7206 0.044616356831 ko05100 Bacterial invasion of epithelial cells 5/145 99/7206 0.0488873834235 ko05146 Amoebiasis 5/145 99/7206 0.0488873834235