ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04146	Peroxisome	26/514	89/7206	2.43544301268e-10
ko00120	Primary bile acid biosynthesis	12/514	20/7206	1.138161496e-09
ko04060	Cytokine-cytokine receptor interaction	32/514	191/7206	4.68904137609e-06
ko00071	Fatty acid degradation	13/514	45/7206	9.30571901652e-06
ko00362	Benzoate degradation	5/514	6/7206	1.02390175359e-05
ko00380	Tryptophan metabolism	13/514	50/7206	3.24861593809e-05
ko04650	Natural killer cell mediated cytotoxicity	19/514	97/7206	4.31588568285e-05
ko05034	Alcoholism	3/514	238/7206	4.98932881588e-05
ko04137	Mitophagy - animal	17/514	82/7206	5.11581920423e-05
ko04380	Osteoclast differentiation	23/514	134/7206	6.33766891354e-05
ko04610	Complement and coagulation cascades	16/514	79/7206	0.000113665412301
ko05321	Inflammatory bowel disease (IBD)	13/514	56/7206	0.00011639643478
ko05150	Staphylococcus aureus infection	10/514	36/7206	0.000145921003212
ko04390	Hippo signaling pathway	2/514	188/7206	0.000151268154122
ko05340	Primary immunodeficiency	9/514	30/7206	0.000164181882224
ko01212	Fatty acid metabolism	13/514	60/7206	0.00024445159896
ko03320	PPAR signaling pathway	14/514	69/7206	0.000295657830909
ko04310	Wnt signaling pathway	2/514	181/7206	0.000331465044777
ko00350	Tyrosine metabolism	9/514	33/7206	0.000364946057045
ko04064	NF-kappa B signaling pathway	17/514	96/7206	0.000386450606904
ko05162	Measles	20/514	120/7206	0.00041262667916
ko03040	Spliceosome	1/514	145/7206	0.000459656015133
ko00051	Fructose and mannose metabolism	10/514	42/7206	0.000572714262512
ko05145	Toxoplasmosis	20/514	126/7206	0.000630086321207
ko05140	Leishmaniasis	14/514	75/7206	0.000721502713483
ko00360	Phenylalanine metabolism	6/514	17/7206	0.000802266967885
ko00590	Arachidonic acid metabolism	11/514	52/7206	0.000900398519907
ko04136	Autophagy - other	8/514	31/7206	0.00115412489883
ko00620	Pyruvate metabolism	10/514	46/7206	0.00122555614962
ko01040	Biosynthesis of unsaturated fatty acids	7/514	25/7206	0.00139735467538
ko03010	Ribosome	1/514	129/7206	0.00147230079445
ko00592	alpha-Linolenic acid metabolism	6/514	19/7206	0.00155553162754
ko05204	Chemical carcinogenesis	10/514	48/7206	0.00172878288871
ko00140	Steroid hormone biosynthesis	9/514	41/7206	0.00198665790303
ko05164	Influenza A	23/514	167/7206	0.00201822203369
ko00640	Propanoate metabolism	8/514	34/7206	0.00219747757438
ko04612	Antigen processing and presentation	13/514	77/7206	0.00284914292128
ko04110	Cell cycle	2/514	145/7206	0.00286696687615
ko00281	Geraniol degradation	3/514	5/7206	0.00323628935533
ko03013	RNA transport	3/514	166/7206	0.0033628813932
ko04659	Th17 cell differentiation	16/514	106/7206	0.00360959771971
ko00950	Isoquinoline alkaloid biosynthesis	4/514	10/7206	0.00379805418295
ko00982	Drug metabolism - cytochrome P450	8/514	37/7206	0.00386798427928
ko00280	Valine, leucine and isoleucine degradation	10/514	54/7206	0.00430263825936
ko04621	NOD-like receptor signaling pathway	21/514	157/7206	0.00438738257187
ko04662	B cell receptor signaling pathway	14/514	88/7206	0.00494624964513
ko04640	Hematopoietic cell lineage	11/514	64/7206	0.00509840131678
ko04728	Dopaminergic synapse	4/514	185/7206	0.00527987998115
ko05330	Allograft rejection	6/514	24/7206	0.00568571297877
ko00980	Metabolism of xenobiotics by cytochrome P450	8/514	40/7206	0.00638163311066
ko05224	Breast cancer	4/514	174/7206	0.00704231691318
ko05332	Graft-versus-host disease	5/514	18/7206	0.00711736810883
ko05168	Herpes simplex infection	23/514	182/7206	0.00772159273487
ko04080	Neuroactive ligand-receptor interaction	17/514	423/7206	0.00832150915918
ko04540	Gap junction	2/514	128/7206	0.00834954357345
ko04658	Th1 and Th2 cell differentiation	14/514	96/7206	0.00854309285218
ko00650	Butanoate metabolism	6/514	26/7206	0.00861295385597
ko00983	Drug metabolism - other enzymes	8/514	42/7206	0.00864115288111
ko04630	Jak-STAT signaling pathway	18/514	132/7206	0.00900182052725
ko04360	Axon guidance	7/514	233/7206	0.00923096470831
ko04910	Insulin signaling pathway	4/514	172/7206	0.00986533431085
ko00330	Arginine and proline metabolism	10/514	61/7206	0.0103672876019
ko04530	Tight junction	7/514	228/7206	0.0123346903069
ko04916	Melanogenesis	3/514	142/7206	0.0128819799247
ko05144	Malaria	8/514	45/7206	0.0130848129299
ko03015	mRNA surveillance pathway	1/514	93/7206	0.0139285966779
ko04010	MAPK signaling pathway	12/514	321/7206	0.014084701932
ko04672	Intestinal immune network for IgA production	7/514	37/7206	0.0142311973754
ko05320	Autoimmune thyroid disease	6/514	29/7206	0.0148213665748
ko00480	Glutathione metabolism	9/514	55/7206	0.0148459304594
ko04620	Toll-like receptor signaling pathway	14/514	100/7206	0.0161366525477
ko05200	Pathways in cancer	22/514	492/7206	0.0178395964585
ko04611	Platelet activation	20/514	163/7206	0.019261043821
ko05167	Kaposi's sarcoma-associated herpesvirus infection	22/514	191/7206	0.022201926621
ko04723	Retrograde endocannabinoid signaling	5/514	175/7206	0.0243721015265
ko00220	Arginine biosynthesis	5/514	24/7206	0.0247937613717
ko04217	Necroptosis	21/514	178/7206	0.0252451491663
ko00062	Fatty acid elongation	6/514	33/7206	0.0271707434998
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	2/514	4/7206	0.0276613885158
ko00643	Styrene degradation	2/514	4/7206	0.0276613885158
ko00072	Synthesis and degradation of ketone bodies	3/514	10/7206	0.0296700910899
ko04350	TGF-beta signaling pathway	2/514	103/7206	0.0330723239842
ko00710	Carbon fixation in photosynthetic organisms	5/514	27/7206	0.0395322166668
ko04622	RIG-I-like receptor signaling pathway	9/514	62/7206	0.0405050587928
ko05203	Viral carcinogenesis	11/514	277/7206	0.0417295933153
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/514	5/7206	0.0439447879561
ko04550	Signaling pathways regulating pluripotency of stem cells	5/514	165/7206	0.0443918672158
ko00270	Cysteine and methionine metabolism	7/514	47/7206	0.047240954355
ko04660	T cell receptor signaling pathway	15/514	124/7206	0.049504125016