ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	176/1145	423/7206	2.47719455297e-39
ko04724	Glutamatergic synapse	84/1145	152/7206	1.6948128111e-29
ko05033	Nicotine addiction	46/1145	56/7206	5.75613659297e-28
ko05032	Morphine addiction	64/1145	110/7206	2.18514191511e-24
ko04727	GABAergic synapse	62/1145	110/7206	1.21946434888e-22
ko04728	Dopaminergic synapse	82/1145	185/7206	1.46689402061e-20
ko04713	Circadian entrainment	67/1145	136/7206	4.75102980758e-20
ko04721	Synaptic vesicle cycle	47/1145	80/7206	1.86581763631e-18
ko04725	Cholinergic synapse	70/1145	160/7206	2.49890093703e-17
ko04723	Retrograde endocannabinoid signaling	74/1145	175/7206	3.03740518487e-17
ko04024	cAMP signaling pathway	100/1145	279/7206	8.39496485894e-17
ko04742	Taste transduction	34/1145	61/7206	8.7778177877e-13
ko04020	Calcium signaling pathway	88/1145	265/7206	1.0822333791e-12
ko04726	Serotonergic synapse	56/1145	137/7206	1.33852727579e-12
ko04744	Phototransduction	24/1145	36/7206	9.77744645319e-12
ko04911	Insulin secretion	49/1145	117/7206	1.2076084932e-11
ko04921	Oxytocin signaling pathway	72/1145	209/7206	1.86086016702e-11
ko05031	Amphetamine addiction	40/1145	91/7206	1.61642264298e-10
ko03040	Spliceosome	1/1145	145/7206	5.15735288073e-10
ko04261	Adrenergic signaling in cardiomyocytes	68/1145	205/7206	6.34044535512e-10
ko04720	Long-term potentiation	40/1145	99/7206	3.3866367913e-09
ko03010	Ribosome	1/1145	129/7206	6.67897224713e-09
ko04970	Salivary secretion	38/1145	95/7206	1.16522946761e-08
ko03013	RNA transport	6/1145	166/7206	8.01115851166e-07
ko05203	Viral carcinogenesis	17/1145	277/7206	8.69365349687e-07
ko04925	Aldosterone synthesis and secretion	37/1145	105/7206	1.05535672485e-06
ko05322	Systemic lupus erythematosus	5/1145	151/7206	1.35486465882e-06
ko05168	Herpes simplex infection	8/1145	182/7206	1.58351104452e-06
ko04971	Gastric acid secretion	35/1145	98/7206	1.88328767958e-06
ko04621	NOD-like receptor signaling pathway	6/1145	157/7206	2.39000369327e-06
ko05030	Cocaine addiction	28/1145	73/7206	2.66018417658e-06
ko04070	Phosphatidylinositol signaling system	37/1145	112/7206	5.61496579357e-06
ko04060	Cytokine-cytokine receptor interaction	10/1145	191/7206	7.61931223558e-06
ko04514	Cell adhesion molecules (CAMs)	41/1145	130/7206	8.11899230154e-06
ko04966	Collecting duct acid secretion	14/1145	26/7206	8.86015897989e-06
ko05164	Influenza A	8/1145	167/7206	1.34028598491e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1145	74/7206	1.45042968048e-05
ko04360	Axon guidance	62/1145	233/7206	2.27182863613e-05
ko04022	cGMP-PKG signaling pathway	57/1145	216/7206	6.11959037443e-05
ko04976	Bile secretion	27/1145	80/7206	7.40570057484e-05
ko04745	Phototransduction - fly	16/1145	38/7206	0.000101876864609
ko04972	Pancreatic secretion	34/1145	111/7206	0.000106285821699
ko04064	NF-kappa B signaling pathway	3/1145	96/7206	0.000110559626604
ko04120	Ubiquitin mediated proteolysis	7/1145	138/7206	0.000136433939715
ko04141	Protein processing in endoplasmic reticulum	12/1145	184/7206	0.000142623592835
ko04072	Phospholipase D signaling pathway	52/1145	197/7206	0.00014711697002
ko04110	Cell cycle	8/1145	145/7206	0.000199835493819
ko04964	Proximal tubule bicarbonate reclamation	13/1145	29/7206	0.000214196005658
ko04010	MAPK signaling pathway	76/1145	321/7206	0.000221765172053
ko04610	Complement and coagulation cascades	2/1145	79/7206	0.000267611758589
ko03008	Ribosome biogenesis in eukaryotes	2/1145	79/7206	0.000267611758589
ko04740	Olfactory transduction	26/1145	80/7206	0.000282425562819
ko04924	Renin secretion	27/1145	86/7206	0.000283780317951
ko05169	Epstein-Barr virus infection	15/1145	206/7206	0.000307034132915
ko04014	Ras signaling pathway	67/1145	279/7206	0.000308667002132
ko05140	Leishmaniasis	2/1145	75/7206	0.000389409955218
ko04612	Antigen processing and presentation	2/1145	77/7206	0.000407820171962
ko04730	Long-term depression	25/1145	78/7206	0.000438246001333
ko05161	Hepatitis B	12/1145	173/7206	0.00048094898018
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/1145	79/7206	0.000484518028659
ko05414	Dilated cardiomyopathy	32/1145	112/7206	0.000597320692638
ko04750	Inflammatory mediator regulation of TRP channels	34/1145	122/7206	0.000653462621004
ko04626	Plant-pathogen interaction	9/1145	18/7206	0.000777462692951
ko00520	Amino sugar and nucleotide sugar metabolism	1/1145	55/7206	0.00132991321497
ko05162	Measles	7/1145	120/7206	0.00143077774066
ko05110	Vibrio cholerae infection	20/1145	63/7206	0.00149054995116
ko04915	Estrogen signaling pathway	35/1145	131/7206	0.00150973305249
ko04540	Gap junction	34/1145	128/7206	0.00203365145094
ko04260	Cardiac muscle contraction	27/1145	98/7206	0.00309454422711
ko04217	Necroptosis	15/1145	178/7206	0.00479208240575
ko03022	Basal transcription factors	1/1145	44/7206	0.00679291621033
ko03420	Nucleotide excision repair	1/1145	46/7206	0.00703491137353
ko05321	Inflammatory bowel disease (IBD)	2/1145	56/7206	0.00880764498813
ko04510	Focal adhesion	24/1145	240/7206	0.00913947157068
ko05205	Proteoglycans in cancer	28/1145	271/7206	0.0107643611353
ko04923	Regulation of lipolysis in adipocytes	21/1145	77/7206	0.0110337152308
ko05166	HTLV-I infection	31/1145	292/7206	0.0110860279717
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1145	59/7206	0.0111198978317
ko04930	Type II diabetes mellitus	16/1145	54/7206	0.013224454305
ko05145	Toxoplasmosis	10/1145	126/7206	0.0132391494488
ko04622	RIG-I-like receptor signaling pathway	3/1145	62/7206	0.0134800569285
ko00965	Betalain biosynthesis	3/1145	4/7206	0.0141077142785
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1145	14/7206	0.0151193949805
ko04630	Jak-STAT signaling pathway	11/1145	132/7206	0.0156176122327
ko05231	Choline metabolism in cancer	32/1145	134/7206	0.0163024595011
ko04658	Th1 and Th2 cell differentiation	7/1145	96/7206	0.016625432374
ko04657	IL-17 signaling pathway	6/1145	87/7206	0.0177170320888
ko05133	Pertussis	6/1145	87/7206	0.0177170320888
ko04710	Circadian rhythm	13/1145	43/7206	0.0185934553303
ko03410	Base excision repair	1/1145	38/7206	0.023190736686
ko03018	RNA degradation	6/1145	84/7206	0.0239694110604
ko02010	ABC transporters	12/1145	39/7206	0.0244911981959
ko00240	Pyrimidine metabolism	9/1145	110/7206	0.0247684174715
ko04114	Oocyte meiosis	32/1145	139/7206	0.0255014436874
ko05219	Bladder cancer	2/1145	48/7206	0.0267048254657
ko04922	Glucagon signaling pathway	30/1145	128/7206	0.0270953902166
ko00562	Inositol phosphate metabolism	22/1145	89/7206	0.0279640610322
ko04371	Apelin signaling pathway	39/1145	177/7206	0.0284405600487
ko04210	Apoptosis	18/1145	180/7206	0.0295703586479
ko05131	Shigellosis	6/1145	82/7206	0.0324072671368
ko04214	Apoptosis - fly	5/1145	72/7206	0.0346808392039
ko04115	p53 signaling pathway	5/1145	74/7206	0.0357604901637
ko05206	MicroRNAs in cancer	18/1145	177/7206	0.0367597447419
ko05410	Hypertrophic cardiomyopathy (HCM)	24/1145	100/7206	0.0373277242254
ko05144	Malaria	2/1145	45/7206	0.0379771116097
ko00071	Fatty acid degradation	2/1145	45/7206	0.0379771116097
ko00280	Valine, leucine and isoleucine degradation	3/1145	54/7206	0.0380253478706
ko00480	Glutathione metabolism	3/1145	55/7206	0.0390014284745
ko04146	Peroxisome	7/1145	89/7206	0.0398131089324
ko04932	Non-alcoholic fatty liver disease (NAFLD)	19/1145	182/7206	0.040040937533
ko04711	Circadian rhythm - fly	5/1145	13/7206	0.0425284519185