ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	145/919	423/7206	1.77116424239e-32
ko04724	Glutamatergic synapse	76/919	152/7206	1.84823734149e-29
ko05033	Nicotine addiction	43/919	56/7206	5.25173263638e-28
ko05032	Morphine addiction	59/919	110/7206	3.80643544794e-25
ko04727	GABAergic synapse	58/919	110/7206	3.14382317717e-24
ko04728	Dopaminergic synapse	73/919	185/7206	1.48123362492e-20
ko04723	Retrograde endocannabinoid signaling	68/919	175/7206	8.72906397428e-19
ko04713	Circadian entrainment	58/919	136/7206	1.90730482441e-18
ko04721	Synaptic vesicle cycle	40/919	80/7206	5.16412458359e-16
ko04744	Phototransduction	25/919	36/7206	4.84684016063e-15
ko04725	Cholinergic synapse	58/919	160/7206	1.3702144091e-14
ko04024	cAMP signaling pathway	82/919	279/7206	5.8212831037e-14
ko04726	Serotonergic synapse	51/919	137/7206	1.68624095568e-13
ko04742	Taste transduction	29/919	61/7206	2.87612846265e-11
ko04020	Calcium signaling pathway	73/919	265/7206	5.0106438572e-11
ko04911	Insulin secretion	41/919	117/7206	3.7411718236e-10
ko04921	Oxytocin signaling pathway	58/919	209/7206	4.66808109618e-09
ko05030	Cocaine addiction	29/919	73/7206	5.43197009668e-09
ko04261	Adrenergic signaling in cardiomyocytes	57/919	205/7206	6.50791595252e-09
ko05031	Amphetamine addiction	32/919	91/7206	2.95379586123e-08
ko03040	Spliceosome	1/919	145/7206	9.17334316287e-08
ko05203	Viral carcinogenesis	11/919	277/7206	7.7265546065e-07
ko04970	Salivary secretion	30/919	95/7206	1.15049564111e-06
ko04720	Long-term potentiation	30/919	99/7206	4.24552592672e-06
ko04060	Cytokine-cytokine receptor interaction	6/919	191/7206	4.83010385624e-06
ko04120	Ubiquitin mediated proteolysis	3/919	138/7206	1.47817987031e-05
ko05164	Influenza A	5/919	167/7206	1.70754797975e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/919	74/7206	2.70410977338e-05
ko04972	Pancreatic secretion	30/919	111/7206	4.06837858757e-05
ko04740	Olfactory transduction	24/919	80/7206	5.20097282994e-05
ko04010	MAPK signaling pathway	66/919	321/7206	5.22104201391e-05
ko04072	Phospholipase D signaling pathway	45/919	197/7206	7.69480091552e-05
ko03013	RNA transport	6/919	166/7206	8.09891722237e-05
ko04260	Cardiac muscle contraction	27/919	98/7206	8.37994888293e-05
ko04022	cGMP-PKG signaling pathway	48/919	216/7206	0.000104159997344
ko05168	Herpes simplex infection	8/919	182/7206	0.000179381781891
ko05169	Epstein-Barr virus infection	10/919	206/7206	0.000183996411543
ko05205	Proteoglycans in cancer	16/919	271/7206	0.000263685960603
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/919	79/7206	0.000264991591464
ko05322	Systemic lupus erythematosus	6/919	151/7206	0.000457866520708
ko04070	Phosphatidylinositol signaling system	28/919	112/7206	0.000465823280657
ko03008	Ribosome biogenesis in eukaryotes	1/919	79/7206	0.0004939474668
ko04964	Proximal tubule bicarbonate reclamation	11/919	29/7206	0.000530516143792
ko04110	Cell cycle	6/919	145/7206	0.00061247344259
ko04925	Aldosterone synthesis and secretion	26/919	105/7206	0.000612512570353
ko05162	Measles	4/919	120/7206	0.000752738158895
ko04966	Collecting duct acid secretion	10/919	26/7206	0.000836231132637
ko04924	Renin secretion	22/919	86/7206	0.000985659113108
ko04971	Gastric acid secretion	24/919	98/7206	0.00119818943009
ko04514	Cell adhesion molecules (CAMs)	30/919	130/7206	0.00121792499573
ko04141	Protein processing in endoplasmic reticulum	10/919	184/7206	0.0015561830123
ko05161	Hepatitis B	9/919	173/7206	0.00164315115089
ko04730	Long-term depression	20/919	78/7206	0.0017270403217
ko04621	NOD-like receptor signaling pathway	8/919	157/7206	0.00225209679576
ko04630	Jak-STAT signaling pathway	6/919	132/7206	0.00225934089353
ko05414	Dilated cardiomyopathy	26/919	112/7206	0.00230535979705
ko04140	Autophagy - animal	9/919	164/7206	0.00288999302864
ko04146	Peroxisome	3/919	89/7206	0.00374524441253
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/919	182/7206	0.00457546972225
ko04915	Estrogen signaling pathway	28/919	131/7206	0.00510413394943
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/919	14/7206	0.00511770693656
ko04976	Bile secretion	19/919	80/7206	0.006162336726
ko00290	Valine, leucine and isoleucine biosynthesis	3/919	4/7206	0.00748433525868
ko03018	RNA degradation	3/919	84/7206	0.00762963947595
ko04064	NF-kappa B signaling pathway	4/919	96/7206	0.00805684622168
ko05231	Choline metabolism in cancer	28/919	134/7206	0.00824097673675
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/919	59/7206	0.00893727164726
ko05166	HTLV-I infection	23/919	292/7206	0.0092011692203
ko05410	Hypertrophic cardiomyopathy (HCM)	22/919	100/7206	0.00939365219029
ko00590	Arachidonic acid metabolism	1/919	52/7206	0.0114733306742
ko04978	Mineral absorption	11/919	40/7206	0.0136740260736
ko05215	Prostate cancer	6/919	111/7206	0.0146146005657
ko04612	Antigen processing and presentation	3/919	77/7206	0.0151102177603
ko04540	Gap junction	26/919	128/7206	0.0152074005572
ko04710	Circadian rhythm	11/919	43/7206	0.019292189238
ko04360	Axon guidance	42/919	233/7206	0.0210475233056
ko00310	Lysine degradation	3/919	73/7206	0.0211139512761
ko04115	p53 signaling pathway	3/919	74/7206	0.0213049241694
ko05140	Leishmaniasis	3/919	75/7206	0.0217551971392
ko00562	Inositol phosphate metabolism	19/919	89/7206	0.0234338521271
ko03420	Nucleotide excision repair	1/919	46/7206	0.025020278283
ko05144	Malaria	1/919	45/7206	0.0250292269058
ko00071	Fatty acid degradation	1/919	45/7206	0.0250292269058
ko05034	Alcoholism	42/919	238/7206	0.0290276045605
ko04974	Protein digestion and absorption	20/919	96/7206	0.0292101605154
ko04218	Cellular senescence	13/919	177/7206	0.0294413889018
ko05206	MicroRNAs in cancer	13/919	177/7206	0.0294413889018
ko04217	Necroptosis	13/919	178/7206	0.0297240804608
ko05145	Toxoplasmosis	8/919	126/7206	0.0300354005497
ko04071	Sphingolipid signaling pathway	30/919	162/7206	0.0315584120384
ko04350	TGF-beta signaling pathway	6/919	103/7206	0.0357408894036
ko03022	Basal transcription factors	1/919	44/7206	0.0376815757027
ko04510	Focal adhesion	20/919	240/7206	0.0382205709132
ko00280	Valine, leucine and isoleucine degradation	2/919	54/7206	0.0405654772802
ko00480	Glutathione metabolism	2/919	55/7206	0.0407103218757
ko05321	Inflammatory bowel disease (IBD)	2/919	56/7206	0.0413905377514
ko04210	Apoptosis	14/919	180/7206	0.041483924166
ko00240	Pyrimidine metabolism	7/919	110/7206	0.0429496503605
ko04014	Ras signaling pathway	47/919	279/7206	0.0435054283898
ko05202	Transcriptional misregulation in cancer	15/919	188/7206	0.0459867733503