ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	50/508	152/7206	1.45936399752e-21
ko04713	Circadian entrainment	45/508	136/7206	1.30401673823e-19
ko04720	Long-term potentiation	34/508	99/7206	1.22138526351e-15
ko04728	Dopaminergic synapse	45/508	185/7206	5.78331458254e-14
ko05031	Amphetamine addiction	29/508	91/7206	1.43083866509e-12
ko04921	Oxytocin signaling pathway	46/508	209/7206	1.47428940613e-12
ko04020	Calcium signaling pathway	53/508	265/7206	1.5319815165e-12
ko04911	Insulin secretion	33/508	117/7206	1.85890336585e-12
ko04261	Adrenergic signaling in cardiomyocytes	43/508	205/7206	4.43595867694e-11
ko04070	Phosphatidylinositol signaling system	30/508	112/7206	8.10092904306e-11
ko04925	Aldosterone synthesis and secretion	28/508	105/7206	3.93335855439e-10
ko05033	Nicotine addiction	20/508	56/7206	4.57969843561e-10
ko04723	Retrograde endocannabinoid signaling	37/508	175/7206	8.45116460894e-10
ko04970	Salivary secretion	26/508	95/7206	9.12145606798e-10
ko04727	GABAergic synapse	28/508	110/7206	1.26255386853e-09
ko04745	Phototransduction - fly	16/508	38/7206	1.53539038335e-09
ko04080	Neuroactive ligand-receptor interaction	64/508	423/7206	3.05979394622e-09
ko05032	Morphine addiction	27/508	110/7206	5.93334589529e-09
ko04730	Long-term depression	22/508	78/7206	9.96190506137e-09
ko04725	Cholinergic synapse	33/508	160/7206	1.36993638547e-08
ko04024	cAMP signaling pathway	46/508	279/7206	5.55378884223e-08
ko04971	Gastric acid secretion	23/508	98/7206	1.96082337349e-07
ko04022	cGMP-PKG signaling pathway	37/508	216/7206	4.09063857179e-07
ko04924	Renin secretion	20/508	86/7206	1.44294146379e-06
ko04922	Glucagon signaling pathway	25/508	128/7206	2.33939101977e-06
ko04726	Serotonergic synapse	26/508	137/7206	2.58707048869e-06
ko05214	Glioma	17/508	79/7206	2.65110816607e-05
ko04740	Olfactory transduction	17/508	80/7206	3.15119535861e-05
ko00562	Inositol phosphate metabolism	18/508	89/7206	3.75117032066e-05
ko05168	Herpes simplex infection	1/508	182/7206	4.60913884139e-05
ko04010	MAPK signaling pathway	42/508	321/7206	7.67193051442e-05
ko04972	Pancreatic secretion	20/508	111/7206	8.02450418031e-05
ko04912	GnRH signaling pathway	21/508	122/7206	0.000106452240181
ko04721	Synaptic vesicle cycle	16/508	80/7206	0.000115812729056
ko04072	Phospholipase D signaling pathway	28/508	197/7206	0.000323632838515
ko04750	Inflammatory mediator regulation of TRP channels	20/508	122/7206	0.000428603824235
ko04260	Cardiac muscle contraction	17/508	98/7206	0.000433173602804
ko04014	Ras signaling pathway	36/508	279/7206	0.000448970208267
ko04360	Axon guidance	31/508	233/7206	0.000584313041679
ko04915	Estrogen signaling pathway	20/508	131/7206	0.000849716817046
ko04012	ErbB signaling pathway	18/508	109/7206	0.000875951020677
ko04626	Plant-pathogen interaction	6/508	18/7206	0.00106382507601
ko03010	Ribosome	1/508	129/7206	0.00144990725941
ko05014	Amyotrophic lateral sclerosis (ALS)	13/508	74/7206	0.00177728291654
ko04114	Oocyte meiosis	20/508	139/7206	0.00207461778482
ko04973	Carbohydrate digestion and absorption	9/508	42/7206	0.00218823220656
ko04514	Cell adhesion molecules (CAMs)	19/508	130/7206	0.00254418739179
ko03040	Spliceosome	2/508	145/7206	0.00284955527862
ko05010	Alzheimer's disease	26/508	202/7206	0.00294199509202
ko05231	Choline metabolism in cancer	19/508	134/7206	0.00313131616909
ko04742	Taste transduction	11/508	61/7206	0.00317699134232
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/508	79/7206	0.00324506196685
ko04270	Vascular smooth muscle contraction	21/508	154/7206	0.0034887962184
ko05030	Cocaine addiction	12/508	73/7206	0.00464518122558
ko04722	Neurotrophin signaling pathway	21/508	160/7206	0.00468262171406
ko04066	HIF-1 signaling pathway	17/508	123/7206	0.0066898233623
ko04916	Melanogenesis	19/508	142/7206	0.00692765896853
ko04960	Aldosterone-regulated sodium reabsorption	8/508	41/7206	0.00694823947755
ko04152	AMPK signaling pathway	21/508	161/7206	0.00709571667719
ko00513	Various types of N-glycan biosynthesis	8/508	42/7206	0.00806824118832
ko04966	Collecting duct acid secretion	6/508	26/7206	0.00814358679974
ko05203	Viral carcinogenesis	9/508	277/7206	0.00822728922789
ko05152	Tuberculosis	23/508	187/7206	0.00838401284358
ko00680	Methane metabolism	7/508	34/7206	0.00840403116508
ko04918	Thyroid hormone synthesis	13/508	86/7206	0.00860836471372
ko05322	Systemic lupus erythematosus	3/508	151/7206	0.00932163346086
ko04350	TGF-beta signaling pathway	1/508	103/7206	0.00996413722292
ko04371	Apelin signaling pathway	22/508	177/7206	0.0103526547797
ko04110	Cell cycle	3/508	145/7206	0.0129789495337
ko05230	Central carbon metabolism in cancer	12/508	81/7206	0.0133069194695
ko05202	Transcriptional misregulation in cancer	5/508	188/7206	0.0133347617038
ko04015	Rap1 signaling pathway	30/508	278/7206	0.0166864298853
ko05169	Epstein-Barr virus infection	6/508	206/7206	0.0177009851339
ko00010	Glycolysis / Gluconeogenesis	11/508	74/7206	0.0182521912081
ko04213	Longevity regulating pathway - multiple species	12/508	86/7206	0.0186438958784
ko00240	Pyrimidine metabolism	2/508	110/7206	0.0235352170175
ko04062	Chemokine signaling pathway	23/508	201/7206	0.0238661404564
ko04071	Sphingolipid signaling pathway	19/508	162/7206	0.0279610512693
ko05410	Hypertrophic cardiomyopathy (HCM)	13/508	100/7206	0.0282603408265
ko04710	Circadian rhythm	7/508	43/7206	0.0291783557599
ko04211	Longevity regulating pathway	15/508	123/7206	0.0319808248629
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/508	59/7206	0.0344667036602
ko05414	Dilated cardiomyopathy	14/508	112/7206	0.0373193659646
ko04744	Phototransduction	6/508	36/7206	0.0380303751952
ko05034	Alcoholism	25/508	238/7206	0.0392049309012
ko05130	Pathogenic Escherichia coli infection	1/508	77/7206	0.0424435925596
ko04612	Antigen processing and presentation	1/508	77/7206	0.0424435925596
ko03008	Ribosome biogenesis in eukaryotes	1/508	79/7206	0.0431415967183
ko04550	Signaling pathways regulating pluripotency of stem cells	5/508	165/7206	0.0436422207067
ko05223	Non-small cell lung cancer	9/508	66/7206	0.0486102404394
ko00512	Mucin type O-glycan biosynthesis	5/508	29/7206	0.0496500697907
ko04964	Proximal tubule bicarbonate reclamation	5/508	29/7206	0.0496500697907