ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04512	ECM-receptor interaction	29/548	79/7206	1.56742261797e-13
ko04060	Cytokine-cytokine receptor interaction	43/548	191/7206	4.61617106009e-11
ko04510	Focal adhesion	49/548	240/7206	8.17507545643e-11
ko04380	Osteoclast differentiation	34/548	134/7206	1.78600109175e-10
ko04621	NOD-like receptor signaling pathway	32/548	157/7206	1.82247939443e-07
ko04933	AGE-RAGE signaling pathway in diabetic complications	28/548	135/7206	7.43498561507e-07
ko04974	Protein digestion and absorption	22/548	96/7206	2.03236598554e-06
ko05164	Influenza A	31/548	167/7206	3.95235027219e-06
ko05034	Alcoholism	3/548	238/7206	1.56752394712e-05
ko04668	TNF signaling pathway	23/548	120/7206	2.83114762983e-05
ko00643	Styrene degradation	4/548	4/7206	3.31086648746e-05
ko04666	Fc gamma R-mediated phagocytosis	23/548	122/7206	3.72807884809e-05
ko05410	Hypertrophic cardiomyopathy (HCM)	20/548	100/7206	4.97938658457e-05
ko00120	Primary bile acid biosynthesis	8/548	20/7206	5.89306307871e-05
ko04064	NF-kappa B signaling pathway	19/548	96/7206	8.87861720393e-05
ko05144	Malaria	12/548	45/7206	9.28988098654e-05
ko00350	Tyrosine metabolism	10/548	33/7206	0.000110992992979
ko04611	Platelet activation	27/548	163/7206	0.000119325390729
ko04810	Regulation of actin cytoskeleton	38/548	264/7206	0.000119616677286
ko05145	Toxoplasmosis	22/548	126/7206	0.000221909336638
ko03013	RNA transport	2/548	166/7206	0.000310617078602
ko05131	Shigellosis	16/548	82/7206	0.000373943301552
ko05146	Amoebiasis	18/548	99/7206	0.000409911657911
ko04620	Toll-like receptor signaling pathway	18/548	100/7206	0.000465419578206
ko05162	Measles	20/548	120/7206	0.000720348540278
ko04657	IL-17 signaling pathway	16/548	87/7206	0.000743832366661
ko05133	Pertussis	16/548	87/7206	0.000743832366661
ko04610	Complement and coagulation cascades	15/548	79/7206	0.000764105936695
ko05414	Dilated cardiomyopathy	19/548	112/7206	0.000837228020519
ko04662	B cell receptor signaling pathway	16/548	88/7206	0.000846819664405
ko04724	Glutamatergic synapse	2/548	152/7206	0.000946584283634
ko00360	Phenylalanine metabolism	6/548	17/7206	0.00112641887858
ko04723	Retrograde endocannabinoid signaling	3/548	175/7206	0.00121830997717
ko04630	Jak-STAT signaling pathway	21/548	132/7206	0.00122324500754
ko03040	Spliceosome	2/548	145/7206	0.00135165900197
ko05132	Salmonella infection	17/548	98/7206	0.00143250871396
ko04660	T cell receptor signaling pathway	20/548	124/7206	0.00157128192508
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	3/548	4/7206	0.00165099850514
ko04622	RIG-I-like receptor signaling pathway	12/548	62/7206	0.00212250644136
ko04658	Th1 and Th2 cell differentiation	16/548	96/7206	0.00267530445127
ko04728	Dopaminergic synapse	4/548	185/7206	0.00272725277458
ko05321	Inflammatory bowel disease (IBD)	11/548	56/7206	0.00284557257471
ko00140	Steroid hormone biosynthesis	9/548	41/7206	0.00308167378509
ko04623	Cytosolic DNA-sensing pathway	9/548	41/7206	0.00308167378509
ko05323	Rheumatoid arthritis	15/548	89/7206	0.00350648045815
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	3/548	5/7206	0.00389418636965
ko05140	Leishmaniasis	13/548	75/7206	0.00391154209502
ko05168	Herpes simplex infection	25/548	182/7206	0.00402715162615
ko05150	Staphylococcus aureus infection	8/548	36/7206	0.00478561547102
ko00920	Sulfur metabolism	4/548	10/7206	0.00479554676396
ko00950	Isoquinoline alkaloid biosynthesis	4/548	10/7206	0.00479554676396
ko04672	Intestinal immune network for IgA production	8/548	37/7206	0.00570922074054
ko00071	Fatty acid degradation	9/548	45/7206	0.00593974978749
ko05340	Primary immunodeficiency	7/548	30/7206	0.00616577253879
ko04110	Cell cycle	3/548	145/7206	0.00653360735876
ko04141	Protein processing in endoplasmic reticulum	5/548	184/7206	0.00708219161858
ko05160	Hepatitis C	21/548	153/7206	0.0078438016463
ko04659	Th17 cell differentiation	16/548	106/7206	0.00815156322307
ko05161	Hepatitis B	23/548	173/7206	0.00815282822927
ko04270	Vascular smooth muscle contraction	21/548	154/7206	0.00815836247184
ko04114	Oocyte meiosis	3/548	139/7206	0.00912043909678
ko04650	Natural killer cell mediated cytotoxicity	15/548	97/7206	0.0101788602217
ko05016	Huntington's disease	7/548	215/7206	0.0122991343068
ko04151	PI3K-Akt signaling pathway	43/548	390/7206	0.0135704718403
ko04217	Necroptosis	23/548	178/7206	0.0137375450812
ko04972	Pancreatic secretion	2/548	111/7206	0.0169878504186
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/548	79/7206	0.0173660306639
ko05205	Proteoglycans in cancer	31/548	271/7206	0.0192483078742
ko04918	Thyroid hormone synthesis	1/548	86/7206	0.0212154696787
ko05222	Small cell lung cancer	13/548	89/7206	0.0234760516356
ko04140	Autophagy - animal	5/548	164/7206	0.0240915512864
ko04916	Melanogenesis	4/548	142/7206	0.0245355631749
ko05167	Kaposi's sarcoma-associated herpesvirus infection	23/548	191/7206	0.0258719262331
ko05134	Legionellosis	11/548	74/7206	0.025986757453
ko04670	Leukocyte transendothelial migration	19/548	151/7206	0.0282550699457
ko04720	Long-term potentiation	2/548	99/7206	0.0332368790071
ko04713	Circadian entrainment	4/548	136/7206	0.0333170410389
ko04120	Ubiquitin mediated proteolysis	4/548	138/7206	0.0335391634206
ko00520	Amino sugar and nucleotide sugar metabolism	9/548	55/7206	0.0343965739315
ko05416	Viral myocarditis	9/548	55/7206	0.0343965739315
ko00051	Fructose and mannose metabolism	7/548	42/7206	0.0371944663864
ko00565	Ether lipid metabolism	7/548	42/7206	0.0371944663864
ko03320	PPAR signaling pathway	10/548	69/7206	0.0388018224481
ko04920	Adipocytokine signaling pathway	12/548	89/7206	0.0432549850128
ko00500	Starch and sucrose metabolism	6/548	35/7206	0.0461370672713
ko03015	mRNA surveillance pathway	2/548	93/7206	0.0464050093332
ko04727	GABAergic synapse	3/548	110/7206	0.046481252073
ko05032	Morphine addiction	3/548	110/7206	0.046481252073
ko04150	mTOR signaling pathway	7/548	184/7206	0.047934364876
ko04390	Hippo signaling pathway	7/548	188/7206	0.0490549401604
ko00281	Geraniol degradation	2/548	5/7206	0.0494700667907