ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	110/728	423/7206	2.96683889567e-22
ko04724	Glutamatergic synapse	52/728	152/7206	3.12713646058e-16
ko05033	Nicotine addiction	29/728	56/7206	4.13482117025e-15
ko04727	GABAergic synapse	40/728	110/7206	9.21324841548e-14
ko04728	Dopaminergic synapse	51/728	185/7206	8.82248567629e-12
ko04260	Cardiac muscle contraction	34/728	98/7206	3.14970569794e-11
ko04721	Synaptic vesicle cycle	28/728	80/7206	1.41153143629e-09
ko04713	Circadian entrainment	38/728	136/7206	2.82884408684e-09
ko05032	Morphine addiction	33/728	110/7206	4.49104817401e-09
ko04261	Adrenergic signaling in cardiomyocytes	49/728	205/7206	5.14115128502e-09
ko04723	Retrograde endocannabinoid signaling	44/728	175/7206	5.88414910046e-09
ko04725	Cholinergic synapse	41/728	160/7206	1.08860086928e-08
ko04742	Taste transduction	22/728	61/7206	4.45037483292e-08
ko04911	Insulin secretion	32/728	117/7206	8.9146869595e-08
ko04744	Phototransduction	16/728	36/7206	1.05260642697e-07
ko05030	Cocaine addiction	23/728	73/7206	3.79042364137e-07
ko04024	cAMP signaling pathway	54/728	279/7206	2.11338993752e-06
ko04740	Olfactory transduction	23/728	80/7206	2.2893659198e-06
ko04060	Cytokine-cytokine receptor interaction	3/728	191/7206	4.16782989843e-06
ko04726	Serotonergic synapse	32/728	137/7206	4.46127571186e-06
ko03040	Spliceosome	1/728	145/7206	4.7951160968e-06
ko05164	Influenza A	2/728	167/7206	5.90186223279e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	21/728	74/7206	7.88403213591e-06
ko04514	Cell adhesion molecules (CAMs)	29/728	130/7206	4.26144703636e-05
ko05168	Herpes simplex infection	4/728	182/7206	5.07173688342e-05
ko05203	Viral carcinogenesis	10/728	277/7206	6.23454425125e-05
ko04950	Maturity onset diabetes of the young	11/728	29/7206	6.50969545494e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/728	79/7206	7.87627154989e-05
ko05162	Measles	1/728	120/7206	8.35271851006e-05
ko04974	Protein digestion and absorption	23/728	96/7206	9.3670001489e-05
ko05410	Hypertrophic cardiomyopathy (HCM)	23/728	100/7206	0.000139273812663
ko03013	RNA transport	4/728	166/7206	0.000211275799873
ko05166	HTLV-I infection	12/728	292/7206	0.000211690785092
ko05031	Amphetamine addiction	21/728	91/7206	0.000276590397502
ko05414	Dilated cardiomyopathy	24/728	112/7206	0.000350732396739
ko04978	Mineral absorption	12/728	40/7206	0.000399989226002
ko04120	Ubiquitin mediated proteolysis	3/728	138/7206	0.00050850629717
ko00564	Glycerophospholipid metabolism	1/728	99/7206	0.000578174705734
ko04150	mTOR signaling pathway	6/728	184/7206	0.000714623313844
ko05322	Systemic lupus erythematosus	4/728	151/7206	0.000871167044824
ko04611	Platelet activation	5/728	163/7206	0.000931667198702
ko04976	Bile secretion	18/728	80/7206	0.00102374371913
ko04970	Salivary secretion	20/728	95/7206	0.00151913360335
ko04964	Proximal tubule bicarbonate reclamation	9/728	29/7206	0.00162467208534
ko04512	ECM-receptor interaction	17/728	79/7206	0.00214735344237
ko04010	MAPK signaling pathway	49/728	321/7206	0.00312482752033
ko03008	Ribosome biogenesis in eukaryotes	1/728	79/7206	0.00404640884866
ko04621	NOD-like receptor signaling pathway	6/728	157/7206	0.00476890543851
ko04973	Carbohydrate digestion and absorption	10/728	42/7206	0.00766347780686
ko04140	Autophagy - animal	7/728	164/7206	0.00845741481118
ko05169	Epstein-Barr virus infection	10/728	206/7206	0.0093528393189
ko04110	Cell cycle	6/728	145/7206	0.0118295642155
ko04730	Long-term depression	15/728	78/7206	0.0126600799782
ko04360	Axon guidance	35/728	233/7206	0.014806257239
ko04138	Autophagy - yeast	2/728	81/7206	0.0152003679151
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/728	59/7206	0.0152676284625
ko04151	PI3K-Akt signaling pathway	54/728	390/7206	0.0152680384976
ko04137	Mitophagy - animal	2/728	82/7206	0.0152929683945
ko04141	Protein processing in endoplasmic reticulum	9/728	184/7206	0.0176209380538
ko05205	Proteoglycans in cancer	16/728	271/7206	0.0177168286309
ko00330	Arginine and proline metabolism	1/728	61/7206	0.0185187543992
ko00600	Sphingolipid metabolism	1/728	63/7206	0.0187640990704
ko04218	Cellular senescence	9/728	177/7206	0.0224255372213
ko04211	Longevity regulating pathway	5/728	123/7206	0.0224953937055
ko04217	Necroptosis	9/728	178/7206	0.0225514668633
ko04660	T cell receptor signaling pathway	5/728	124/7206	0.0227486639756
ko05152	Tuberculosis	10/728	187/7206	0.0264009085814
ko04921	Oxytocin signaling pathway	31/728	209/7206	0.0264450970484
ko01212	Fatty acid metabolism	1/728	60/7206	0.0280576073343
ko05161	Hepatitis B	9/728	173/7206	0.0291629019559
ko04214	Apoptosis - fly	2/728	72/7206	0.0307265939864
ko05134	Legionellosis	2/728	74/7206	0.0309506387871
ko05140	Leishmaniasis	2/728	75/7206	0.0314470059246
ko04914	Progesterone-mediated oocyte maturation	4/728	104/7206	0.0316188673299
ko00280	Valine, leucine and isoleucine degradation	1/728	54/7206	0.0395091722744
ko00350	Tyrosine metabolism	7/728	33/7206	0.0433364949549
ko04962	Vasopressin-regulated water reabsorption	11/728	58/7206	0.0439356083206
ko03018	RNA degradation	3/728	84/7206	0.044009321522
ko00430	Taurine and hypotaurine metabolism	4/728	14/7206	0.0454138386418