ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	141/932	423/7206	2.09476538023e-29
ko05033	Nicotine addiction	43/932	56/7206	9.49242956193e-28
ko04724	Glutamatergic synapse	73/932	152/7206	1.63511086503e-26
ko04727	GABAergic synapse	54/932	110/7206	1.965858867e-20
ko04721	Synaptic vesicle cycle	45/932	80/7206	2.60230001333e-20
ko05032	Morphine addiction	53/932	110/7206	1.32579585185e-19
ko04728	Dopaminergic synapse	70/932	185/7206	3.22383579975e-18
ko04725	Cholinergic synapse	62/932	160/7206	7.5884519953e-17
ko04713	Circadian entrainment	55/932	136/7206	4.9355573262e-16
ko04723	Retrograde endocannabinoid signaling	63/932	175/7206	2.77313181625e-15
ko04744	Phototransduction	25/932	36/7206	6.76926649085e-15
ko04024	cAMP signaling pathway	79/932	279/7206	3.70468869497e-12
ko04911	Insulin secretion	43/932	117/7206	3.67701524213e-11
ko04742	Taste transduction	28/932	61/7206	2.50730718833e-10
ko04726	Serotonergic synapse	46/932	137/7206	2.64900201492e-10
ko05203	Viral carcinogenesis	9/932	277/7206	2.51138911772e-08
ko04921	Oxytocin signaling pathway	55/932	209/7206	1.53361104686e-07
ko05031	Amphetamine addiction	31/932	91/7206	1.55265998958e-07
ko05030	Cocaine addiction	26/932	73/7206	5.82049906976e-07
ko03040	Spliceosome	2/932	145/7206	6.02386765167e-07
ko04060	Cytokine-cytokine receptor interaction	5/932	191/7206	9.0300892534e-07
ko05164	Influenza A	4/932	167/7206	2.05940957452e-06
ko04120	Ubiquitin mediated proteolysis	2/932	138/7206	2.07174156244e-06
ko04261	Adrenergic signaling in cardiomyocytes	51/932	205/7206	2.31406575888e-06
ko04020	Calcium signaling pathway	61/932	265/7206	3.84958421371e-06
ko04740	Olfactory transduction	26/932	80/7206	4.23905639457e-06
ko04514	Cell adhesion molecules (CAMs)	36/932	130/7206	7.42393197614e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/932	74/7206	1.02815358866e-05
ko04720	Long-term potentiation	29/932	99/7206	1.31514323425e-05
ko03013	RNA transport	5/932	166/7206	1.74121527182e-05
ko05322	Systemic lupus erythematosus	4/932	151/7206	2.05964449719e-05
ko04621	NOD-like receptor signaling pathway	5/932	157/7206	3.42733145932e-05
ko04966	Collecting duct acid secretion	12/932	26/7206	3.45705012951e-05
ko05168	Herpes simplex infection	7/932	182/7206	4.42830639394e-05
ko04360	Axon guidance	52/932	233/7206	5.92108837237e-05
ko05205	Proteoglycans in cancer	15/932	271/7206	6.4701237242e-05
ko04970	Salivary secretion	27/932	95/7206	7.06068770151e-05
ko04964	Proximal tubule bicarbonate reclamation	12/932	29/7206	0.000128032614712
ko05166	HTLV-I infection	18/932	292/7206	0.000170941691966
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/932	79/7206	0.000317120820445
ko05169	Epstein-Barr virus infection	11/932	206/7206	0.000449964057368
ko04972	Pancreatic secretion	28/932	111/7206	0.000474935932429
ko05162	Measles	4/932	120/7206	0.000506406042433
ko03008	Ribosome biogenesis in eukaryotes	1/932	79/7206	0.000514499849893
ko04010	MAPK signaling pathway	63/932	321/7206	0.000613238064376
ko04260	Cardiac muscle contraction	25/932	98/7206	0.000667649821848
ko04971	Gastric acid secretion	25/932	98/7206	0.000667649821848
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/932	14/7206	0.000888683201718
ko04730	Long-term depression	21/932	78/7206	0.000913948490697
ko04925	Aldosterone synthesis and secretion	26/932	105/7206	0.00100793098244
ko04141	Protein processing in endoplasmic reticulum	10/932	184/7206	0.00113610926727
ko05161	Hepatitis B	9/932	173/7206	0.00118250217937
ko04110	Cell cycle	7/932	145/7206	0.00163845642242
ko04064	NF-kappa B signaling pathway	3/932	96/7206	0.00184796981113
ko04640	Hematopoietic cell lineage	1/932	64/7206	0.00235272604536
ko04612	Antigen processing and presentation	2/932	77/7206	0.0031786983791
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/932	182/7206	0.00340815335479
ko04976	Bile secretion	20/932	80/7206	0.00360297187093
ko04146	Peroxisome	3/932	89/7206	0.00373268723669
ko05140	Leishmaniasis	2/932	75/7206	0.00475536234684
ko04630	Jak-STAT signaling pathway	7/932	132/7206	0.00564568175368
ko04745	Phototransduction - fly	11/932	38/7206	0.00696263916338
ko00280	Valine, leucine and isoleucine degradation	1/932	54/7206	0.00771498398939
ko00480	Glutathione metabolism	1/932	55/7206	0.00772305651559
ko03018	RNA degradation	3/932	84/7206	0.00780504711163
ko05418	Fluid shear stress and atherosclerosis	11/932	173/7206	0.00787331590837
ko04022	cGMP-PKG signaling pathway	41/932	216/7206	0.00983074402055
ko00590	Arachidonic acid metabolism	1/932	52/7206	0.0114561302364
ko04140	Autophagy - animal	11/932	164/7206	0.0131878314307
ko00561	Glycerolipid metabolism	2/932	63/7206	0.0137878862727
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	8/932	26/7206	0.0139116195849
ko04014	Ras signaling pathway	50/932	279/7206	0.0139180825638
ko00240	Pyrimidine metabolism	6/932	110/7206	0.0145131698774
ko05215	Prostate cancer	6/932	111/7206	0.014595542037
ko01524	Platinum drug resistance	3/932	76/7206	0.0150269851282
ko04924	Renin secretion	19/932	86/7206	0.0151310772616
ko04657	IL-17 signaling pathway	4/932	87/7206	0.015275282848
ko05133	Pertussis	4/932	87/7206	0.015275282848
ko00260	Glycine, serine and threonine metabolism	1/932	48/7206	0.0168368743087
ko05219	Bladder cancer	1/932	48/7206	0.0168368743087
ko04668	TNF signaling pathway	7/932	120/7206	0.0186666883342
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/932	59/7206	0.0188617753571
ko00330	Arginine and proline metabolism	2/932	61/7206	0.0199272697696
ko05110	Vibrio cholerae infection	15/932	63/7206	0.0211338459256
ko05145	Toxoplasmosis	8/932	126/7206	0.0225543874933
ko04930	Type II diabetes mellitus	13/932	54/7206	0.0228427179078
ko04217	Necroptosis	13/932	178/7206	0.023039911619
ko00071	Fatty acid degradation	1/932	45/7206	0.024829823573
ko03420	Nucleotide excision repair	1/932	46/7206	0.0251167546225
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/932	15/7206	0.0352837798594
ko03022	Basal transcription factors	1/932	44/7206	0.038304261065
ko04218	Cellular senescence	14/932	177/7206	0.0413252388958
ko04210	Apoptosis	14/932	180/7206	0.0418864125127
ko05321	Inflammatory bowel disease (IBD)	2/932	56/7206	0.0421070074508
ko04070	Phosphatidylinositol signaling system	22/932	112/7206	0.0452396735793
ko01200	Carbon metabolism	9/932	128/7206	0.0454892861341
ko04658	Th1 and Th2 cell differentiation	6/932	96/7206	0.0467183404958
ko05016	Huntington's disease	18/932	215/7206	0.0490795721491