ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	135/959	423/7206	9.92826746397e-25
ko04724	Glutamatergic synapse	60/959	152/7206	3.44081557757e-16
ko05033	Nicotine addiction	33/959	56/7206	1.12080867338e-15
ko04723	Retrograde endocannabinoid signaling	61/959	175/7206	1.59788245637e-13
ko04020	Calcium signaling pathway	78/959	265/7206	2.01671632567e-12
ko04713	Circadian entrainment	50/959	136/7206	2.67891223965e-12
ko05032	Morphine addiction	42/959	110/7206	3.78136735284e-11
ko04911	Insulin secretion	42/959	117/7206	3.70024348185e-10
ko04727	GABAergic synapse	40/959	110/7206	6.25285454511e-10
ko04725	Cholinergic synapse	51/959	160/7206	7.58623201767e-10
ko04921	Oxytocin signaling pathway	61/959	209/7206	1.20516923898e-09
ko04022	cGMP-PKG signaling pathway	62/959	216/7206	1.32476729211e-09
ko04024	cAMP signaling pathway	74/959	279/7206	2.34236638267e-09
ko04728	Dopaminergic synapse	54/959	185/7206	8.38732105821e-09
ko04742	Taste transduction	26/959	61/7206	1.42961700466e-08
ko05322	Systemic lupus erythematosus	1/959	151/7206	1.58475838599e-08
ko04970	Salivary secretion	33/959	95/7206	7.2540062696e-08
ko04726	Serotonergic synapse	42/959	137/7206	7.96695527139e-08
ko03010	Ribosome	1/959	129/7206	2.88813661011e-07
ko04261	Adrenergic signaling in cardiomyocytes	54/959	205/7206	5.50944117679e-07
ko05168	Herpes simplex infection	5/959	182/7206	1.23811766048e-06
ko04721	Synaptic vesicle cycle	27/959	80/7206	2.12691487043e-06
ko00010	Glycolysis / Gluconeogenesis	25/959	74/7206	4.94958833959e-06
ko05031	Amphetamine addiction	29/959	91/7206	5.45572029329e-06
ko05010	Alzheimer's disease	50/959	202/7206	7.75152956342e-06
ko05203	Viral carcinogenesis	14/959	277/7206	7.75169028001e-06
ko04060	Cytokine-cytokine receptor interaction	7/959	191/7206	1.11653023665e-05
ko03013	RNA transport	6/959	166/7206	3.90576454526e-05
ko01200	Carbon metabolism	34/959	128/7206	5.62242579222e-05
ko04260	Cardiac muscle contraction	28/959	98/7206	6.03992070177e-05
ko04971	Gastric acid secretion	28/959	98/7206	6.03992070177e-05
ko03040	Spliceosome	5/959	145/7206	9.8433054139e-05
ko04110	Cell cycle	5/959	145/7206	9.8433054139e-05
ko05164	Influenza A	7/959	167/7206	0.000118186671862
ko04745	Phototransduction - fly	14/959	38/7206	0.000215367502075
ko04925	Aldosterone synthesis and secretion	28/959	105/7206	0.000221165873582
ko00680	Methane metabolism	13/959	34/7206	0.000234938941085
ko04922	Glucagon signaling pathway	32/959	128/7206	0.00031391793487
ko03008	Ribosome biogenesis in eukaryotes	1/959	79/7206	0.000320488387759
ko04740	Olfactory transduction	23/959	80/7206	0.000338791000368
ko04630	Jak-STAT signaling pathway	5/959	132/7206	0.000395217829704
ko05030	Cocaine addiction	21/959	73/7206	0.000401629518875
ko04744	Phototransduction	13/959	36/7206	0.000452816350747
ko05140	Leishmaniasis	1/959	75/7206	0.000466371247091
ko04720	Long-term potentiation	26/959	99/7206	0.000480699025281
ko00190	Oxidative phosphorylation	31/959	127/7206	0.000549057462015
ko04972	Pancreatic secretion	28/959	111/7206	0.000604014052414
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/959	79/7206	0.000607724482698
ko04270	Vascular smooth muscle contraction	36/959	154/7206	0.000663850242572
ko04371	Apelin signaling pathway	40/959	177/7206	0.000672354152357
ko05012	Parkinson's disease	36/959	155/7206	0.000697309476705
ko05014	Amyotrophic lateral sclerosis (ALS)	21/959	74/7206	0.0007608502858
ko04120	Ubiquitin mediated proteolysis	6/959	138/7206	0.000848881459627
ko04710	Circadian rhythm	14/959	43/7206	0.000918175427744
ko05166	HTLV-I infection	21/959	292/7206	0.00106960794038
ko04730	Long-term depression	21/959	78/7206	0.00115778371891
ko04010	MAPK signaling pathway	63/959	321/7206	0.00131675381347
ko05410	Hypertrophic cardiomyopathy (HCM)	25/959	100/7206	0.00152630063876
ko05162	Measles	5/959	120/7206	0.00156683403957
ko00710	Carbon fixation in photosynthetic organisms	10/959	27/7206	0.00164383623324
ko01230	Biosynthesis of amino acids	22/959	85/7206	0.00182105700453
ko04150	mTOR signaling pathway	11/959	184/7206	0.00191093016014
ko00620	Pyruvate metabolism	14/959	46/7206	0.00191383496834
ko04924	Renin secretion	22/959	86/7206	0.00200043807613
ko04514	Cell adhesion molecules (CAMs)	30/959	130/7206	0.00238883355726
ko04964	Proximal tubule bicarbonate reclamation	10/959	29/7206	0.00304067343226
ko05169	Epstein-Barr virus infection	14/959	206/7206	0.00345720629918
ko04657	IL-17 signaling pathway	3/959	87/7206	0.00369843556266
ko04974	Protein digestion and absorption	23/959	96/7206	0.00377700945255
ko04930	Type II diabetes mellitus	15/959	54/7206	0.00404644434496
ko00020	Citrate cycle (TCA cycle)	11/959	35/7206	0.00435029267744
ko05161	Hepatitis B	11/959	173/7206	0.00441653912005
ko05414	Dilated cardiomyopathy	26/959	112/7206	0.00446049140131
ko04626	Plant-pathogen interaction	7/959	18/7206	0.00605989656656
ko00030	Pentose phosphate pathway	10/959	32/7206	0.00674473305871
ko05200	Pathways in cancer	47/959	492/7206	0.0107864206875
ko05220	Chronic myeloid leukemia	4/959	85/7206	0.0151158027318
ko04978	Mineral absorption	11/959	40/7206	0.0161644934676
ko04621	NOD-like receptor signaling pathway	11/959	157/7206	0.0169633687446
ko05205	Proteoglycans in cancer	23/959	271/7206	0.017359382571
ko04960	Aldosterone-regulated sodium reabsorption	11/959	41/7206	0.0184034170599
ko04550	Signaling pathways regulating pluripotency of stem cells	12/959	165/7206	0.0197995478853
ko04141	Protein processing in endoplasmic reticulum	14/959	184/7206	0.0203827601101
ko05224	Breast cancer	13/959	174/7206	0.0230399633355
ko00230	Purine metabolism	37/959	194/7206	0.023699779661
ko05215	Prostate cancer	7/959	111/7206	0.0241938119285
ko03022	Basal transcription factors	1/959	44/7206	0.0245679686737
ko04540	Gap junction	26/959	128/7206	0.0248105099976
ko03420	Nucleotide excision repair	1/959	46/7206	0.0259237988758
ko04620	Toll-like receptor signaling pathway	6/959	100/7206	0.0259845693533
ko00520	Amino sugar and nucleotide sugar metabolism	2/959	55/7206	0.0279930858648
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/959	59/7206	0.0311800659
ko04217	Necroptosis	14/959	178/7206	0.0328918640281
ko00980	Metabolism of xenobiotics by cytochrome P450	1/959	40/7206	0.0362448633572
ko04212	Longevity regulating pathway - worm	5/959	87/7206	0.0375496218666
ko01524	Platinum drug resistance	4/959	76/7206	0.0397923696665
ko04913	Ovarian steroidogenesis	3/959	63/7206	0.0405469961195
ko04144	Endocytosis	33/959	342/7206	0.0412829811604
ko01521	EGFR tyrosine kinase inhibitor resistance	7/959	106/7206	0.042525357329
ko04660	T cell receptor signaling pathway	9/959	124/7206	0.0450236469916
ko01522	Endocrine resistance	9/959	124/7206	0.0450236469916
ko04140	Autophagy - animal	13/959	164/7206	0.0469071651215
ko04064	NF-kappa B signaling pathway	6/959	96/7206	0.0472969893952