ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	116/796	423/7206	4.02683338156e-22
ko05033	Nicotine addiction	35/796	56/7206	2.2639503749e-20
ko04724	Glutamatergic synapse	58/796	152/7206	1.00368989591e-18
ko04721	Synaptic vesicle cycle	37/796	80/7206	1.48311586156e-15
ko04728	Dopaminergic synapse	57/796	185/7206	1.24447329918e-13
ko04713	Circadian entrainment	45/796	136/7206	3.28016262648e-12
ko04727	GABAergic synapse	39/796	110/7206	8.38059267237e-12
ko05032	Morphine addiction	39/796	110/7206	8.38059267237e-12
ko04360	Axon guidance	61/796	233/7206	7.02045170577e-11
ko04723	Retrograde endocannabinoid signaling	48/796	175/7206	1.01286362459e-09
ko04725	Cholinergic synapse	45/796	160/7206	1.42792549408e-09
ko04024	cAMP signaling pathway	63/796	279/7206	1.51059355156e-08
ko05030	Cocaine addiction	25/796	73/7206	1.0739902463e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/796	74/7206	1.45512749985e-07
ko04911	Insulin secretion	33/796	117/7206	2.1290994116e-07
ko05031	Amphetamine addiction	28/796	91/7206	2.47356834201e-07
ko04514	Cell adhesion molecules (CAMs)	35/796	130/7206	5.31348794076e-07
ko04261	Adrenergic signaling in cardiomyocytes	47/796	205/7206	7.03217003314e-07
ko03040	Spliceosome	1/796	145/7206	1.32263173572e-06
ko04010	MAPK signaling pathway	63/796	321/7206	3.96911250029e-06
ko04726	Serotonergic synapse	33/796	137/7206	1.14970758927e-05
ko04060	Cytokine-cytokine receptor interaction	5/796	191/7206	1.96384399606e-05
ko04120	Ubiquitin mediated proteolysis	2/796	138/7206	2.55063534099e-05
ko05203	Viral carcinogenesis	11/796	277/7206	3.24496012458e-05
ko03013	RNA transport	4/796	166/7206	4.7152771679e-05
ko05168	Herpes simplex infection	5/796	182/7206	5.80021856815e-05
ko04742	Taste transduction	18/796	61/7206	6.47956033606e-05
ko04950	Maturity onset diabetes of the young	11/796	29/7206	0.00014763099966
ko04720	Long-term potentiation	24/796	99/7206	0.000150093144626
ko04970	Salivary secretion	23/796	95/7206	0.000211573125637
ko04966	Collecting duct acid secretion	10/796	26/7206	0.000259270765358
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/796	14/7206	0.00033337834641
ko01200	Carbon metabolism	3/796	128/7206	0.000497504881803
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/796	79/7206	0.000849668047549
ko03018	RNA degradation	1/796	84/7206	0.00122317671981
ko04921	Oxytocin signaling pathway	38/796	209/7206	0.00162602723897
ko03008	Ribosome biogenesis in eukaryotes	1/796	79/7206	0.00175685959213
ko04621	NOD-like receptor signaling pathway	6/796	157/7206	0.00179434499818
ko05164	Influenza A	7/796	167/7206	0.00247059437826
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/796	182/7206	0.00247413586011
ko04730	Long-term depression	18/796	78/7206	0.00282939604785
ko04146	Peroxisome	2/796	89/7206	0.00345609070915
ko05322	Systemic lupus erythematosus	6/796	151/7206	0.00347396901581
ko04022	cGMP-PKG signaling pathway	38/796	216/7206	0.00385057252681
ko04540	Gap junction	25/796	128/7206	0.00402589824478
ko04744	Phototransduction	10/796	36/7206	0.00445501510095
ko05162	Measles	4/796	120/7206	0.00461042076496
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/796	59/7206	0.00510961080839
ko04141	Protein processing in endoplasmic reticulum	9/796	184/7206	0.0056836224083
ko05146	Amoebiasis	3/796	99/7206	0.00572570025418
ko04924	Renin secretion	18/796	86/7206	0.0080681610651
ko04064	NF-kappa B signaling pathway	3/796	96/7206	0.00809078495259
ko04014	Ras signaling pathway	45/796	279/7206	0.00828271858824
ko00240	Pyrimidine metabolism	4/796	110/7206	0.00854092733989
ko05205	Proteoglycans in cancer	17/796	271/7206	0.00982425075627
ko04915	Estrogen signaling pathway	24/796	131/7206	0.0109538257932
ko04964	Proximal tubule bicarbonate reclamation	8/796	29/7206	0.011084453919
ko00561	Glycerolipid metabolism	1/796	63/7206	0.0130670242776
ko04972	Pancreatic secretion	21/796	111/7206	0.0134272082272
ko04260	Cardiac muscle contraction	19/796	98/7206	0.0136844659146
ko04015	Rap1 signaling pathway	44/796	278/7206	0.0142262028277
ko00010	Glycolysis / Gluconeogenesis	2/796	74/7206	0.01472701743
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/796	15/7206	0.0189496172982
ko04974	Protein digestion and absorption	18/796	96/7206	0.021084670518
ko04214	Apoptosis - fly	2/796	72/7206	0.0213853753964
ko00310	Lysine degradation	2/796	73/7206	0.0219076688302
ko05110	Vibrio cholerae infection	13/796	63/7206	0.0238308940489
ko05169	Epstein-Barr virus infection	13/796	206/7206	0.0241062284644
ko05224	Breast cancer	29/796	174/7206	0.0264614719433
ko00280	Valine, leucine and isoleucine degradation	1/796	54/7206	0.0266946206534
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/796	92/7206	0.0287728522195
ko04138	Autophagy - yeast	3/796	81/7206	0.0310918222437
ko04962	Vasopressin-regulated water reabsorption	12/796	58/7206	0.0316436426347
ko04217	Necroptosis	11/796	178/7206	0.0385150994426
ko04913	Ovarian steroidogenesis	2/796	63/7206	0.0424196699264
ko05213	Endometrial cancer	12/796	62/7206	0.0424392507313
ko04611	Platelet activation	10/796	163/7206	0.0426101418409
ko04140	Autophagy - animal	10/796	164/7206	0.0427944365783
ko04640	Hematopoietic cell lineage	2/796	64/7206	0.0427963526028
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/796	8/7206	0.0491585314824