ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	151/879	423/7206	1.15972047476e-38
ko05033	Nicotine addiction	42/879	56/7206	1.8656412586e-27
ko04724	Glutamatergic synapse	70/879	152/7206	1.20740955935e-25
ko04721	Synaptic vesicle cycle	45/879	80/7206	2.32855148368e-21
ko04728	Dopaminergic synapse	68/879	185/7206	2.50156322542e-18
ko04727	GABAergic synapse	49/879	110/7206	1.63880406174e-17
ko05032	Morphine addiction	49/879	110/7206	1.63880406174e-17
ko04725	Cholinergic synapse	58/879	160/7206	1.79843421642e-15
ko04713	Circadian entrainment	52/879	136/7206	4.24068378257e-15
ko04723	Retrograde endocannabinoid signaling	59/879	175/7206	4.38987174866e-14
ko04024	cAMP signaling pathway	77/879	279/7206	1.04641834728e-12
ko04726	Serotonergic synapse	46/879	137/7206	3.52672390991e-11
ko04911	Insulin secretion	40/879	117/7206	3.71024687048e-10
ko04742	Taste transduction	27/879	61/7206	3.81261036098e-10
ko04921	Oxytocin signaling pathway	57/879	209/7206	2.12416118222e-09
ko05031	Amphetamine addiction	33/879	91/7206	2.3649220926e-09
ko04261	Adrenergic signaling in cardiomyocytes	56/879	205/7206	2.94355590469e-09
ko04720	Long-term potentiation	34/879	99/7206	6.88931373195e-09
ko04020	Calcium signaling pathway	64/879	265/7206	4.53840379656e-08
ko04360	Axon guidance	58/879	233/7206	6.09877782295e-08
ko05030	Cocaine addiction	26/879	73/7206	1.80982688869e-07
ko03040	Spliceosome	1/879	145/7206	2.26987613572e-07
ko04060	Cytokine-cytokine receptor interaction	4/879	191/7206	4.87777566413e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/879	74/7206	9.82813931607e-07
ko04010	MAPK signaling pathway	69/879	321/7206	1.81977563016e-06
ko04514	Cell adhesion molecules (CAMs)	35/879	130/7206	4.09817485678e-06
ko04120	Ubiquitin mediated proteolysis	2/879	138/7206	4.76838488658e-06
ko04970	Salivary secretion	28/879	95/7206	4.87356562295e-06
ko05164	Influenza A	4/879	167/7206	6.82504403833e-06
ko05203	Viral carcinogenesis	12/879	277/7206	8.39195492358e-06
ko05168	Herpes simplex infection	5/879	182/7206	8.84487689791e-06
ko04621	NOD-like receptor signaling pathway	4/879	157/7206	2.06949288947e-05
ko04744	Phototransduction	14/879	36/7206	4.13425904727e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/879	79/7206	4.20763173102e-05
ko03013	RNA transport	5/879	166/7206	5.48906409176e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/879	14/7206	7.24962852144e-05
ko04966	Collecting duct acid secretion	11/879	26/7206	0.000113339931949
ko04971	Gastric acid secretion	26/879	98/7206	0.0001181855394
ko05322	Systemic lupus erythematosus	5/879	151/7206	0.000214225901096
ko04540	Gap junction	30/879	128/7206	0.000322715526951
ko04730	Long-term depression	21/879	78/7206	0.000339004781811
ko04141	Protein processing in endoplasmic reticulum	8/879	184/7206	0.000354029641453
ko04925	Aldosterone synthesis and secretion	26/879	105/7206	0.000398000411542
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/879	182/7206	0.000495554211035
ko03008	Ribosome biogenesis in eukaryotes	1/879	79/7206	0.000757791167751
ko04612	Antigen processing and presentation	1/879	77/7206	0.00119029617286
ko04924	Renin secretion	21/879	86/7206	0.00139385590943
ko04014	Ras signaling pathway	52/879	279/7206	0.00144003996821
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/879	59/7206	0.00186253130458
ko04972	Pancreatic secretion	25/879	111/7206	0.00190288662547
ko05414	Dilated cardiomyopathy	25/879	112/7206	0.00208543902768
ko04915	Estrogen signaling pathway	28/879	131/7206	0.00269347589241
ko05205	Proteoglycans in cancer	18/879	271/7206	0.00320357205605
ko05110	Vibrio cholerae infection	16/879	63/7206	0.0032196658742
ko04740	Olfactory transduction	19/879	80/7206	0.00323870250695
ko04640	Hematopoietic cell lineage	1/879	64/7206	0.00362916404077
ko04064	NF-kappa B signaling pathway	3/879	96/7206	0.00402407951751
ko04022	cGMP-PKG signaling pathway	41/879	216/7206	0.00407768059549
ko05162	Measles	5/879	120/7206	0.00440979567977
ko04260	Cardiac muscle contraction	22/879	98/7206	0.00442029447187
ko04745	Phototransduction - fly	11/879	38/7206	0.00444738286034
ko00330	Arginine and proline metabolism	1/879	61/7206	0.00536696626688
ko01200	Carbon metabolism	6/879	128/7206	0.00598798968126
ko05161	Hepatitis B	10/879	173/7206	0.00656006601637
ko05169	Epstein-Barr virus infection	13/879	206/7206	0.00668126360094
ko05140	Leishmaniasis	2/879	75/7206	0.00690415794731
ko04072	Phospholipase D signaling pathway	37/879	197/7206	0.00760465738014
ko04146	Peroxisome	3/879	89/7206	0.0080334518967
ko04391	Hippo signaling pathway - fly	20/879	90/7206	0.0083361527405
ko04110	Cell cycle	8/879	145/7206	0.00995770985917
ko04214	Apoptosis - fly	2/879	72/7206	0.0100194158706
ko04217	Necroptosis	11/879	178/7206	0.0103967763818
ko03018	RNA degradation	3/879	84/7206	0.0109583130753
ko04015	Rap1 signaling pathway	48/879	278/7206	0.0113676770352
ko00240	Pyrimidine metabolism	5/879	110/7206	0.0115737556918
ko00480	Glutathione metabolism	1/879	55/7206	0.0117644531795
ko05321	Inflammatory bowel disease (IBD)	1/879	56/7206	0.0120137751841
ko04722	Neurotrophin signaling pathway	30/879	160/7206	0.0142036767876
ko04626	Plant-pathogen interaction	6/879	18/7206	0.016453544759
ko04750	Inflammatory mediator regulation of TRP channels	24/879	122/7206	0.016735535843
ko00590	Arachidonic acid metabolism	1/879	52/7206	0.017431141152
ko04964	Proximal tubule bicarbonate reclamation	8/879	29/7206	0.0195176978381
ko01524	Platinum drug resistance	3/879	76/7206	0.0214825159475
ko05166	HTLV-I infection	23/879	292/7206	0.0219977324757
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/879	15/7206	0.028107811335
ko05146	Amoebiasis	5/879	99/7206	0.0288718450931
ko00310	Lysine degradation	3/879	73/7206	0.0300313551197
ko00561	Glycerolipid metabolism	2/879	63/7206	0.0304157056997
ko04630	Jak-STAT signaling pathway	8/879	132/7206	0.0305786697935
ko04668	TNF signaling pathway	7/879	120/7206	0.0334868487085
ko04930	Type II diabetes mellitus	12/879	54/7206	0.0342448430297
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/879	92/7206	0.0365048222357
ko03022	Basal transcription factors	1/879	44/7206	0.0372913004601
ko05144	Malaria	1/879	45/7206	0.0374829525658
ko00071	Fatty acid degradation	1/879	45/7206	0.0374829525658
ko03420	Nucleotide excision repair	1/879	46/7206	0.0382619588148
ko05145	Toxoplasmosis	8/879	126/7206	0.0395320953292
ko04070	Phosphatidylinositol signaling system	21/879	112/7206	0.0406146044676
ko05410	Hypertrophic cardiomyopathy (HCM)	19/879	100/7206	0.0444268443666