ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04610	Complement and coagulation cascades	26/515	79/7206	1.26005794797e-11
ko04721	Synaptic vesicle cycle	25/515	80/7206	1.12820926276e-10
ko05033	Nicotine addiction	20/515	56/7206	5.84146483003e-10
ko04080	Neuroactive ligand-receptor interaction	65/515	423/7206	2.07155425643e-09
ko04724	Glutamatergic synapse	33/515	152/7206	4.97097991799e-09
ko04727	GABAergic synapse	27/515	110/7206	7.97785325421e-09
ko04728	Dopaminergic synapse	35/515	185/7206	7.13901593529e-08
ko04713	Circadian entrainment	28/515	136/7206	2.43663245858e-07
ko04950	Maturity onset diabetes of the young	12/515	29/7206	2.63659223166e-07
ko04723	Retrograde endocannabinoid signaling	31/515	175/7206	1.80068548704e-06
ko05032	Morphine addiction	23/515	110/7206	2.20821537673e-06
ko04145	Phagosome	29/515	162/7206	3.13014049302e-06
ko04060	Cytokine-cytokine receptor interaction	1/515	191/7206	2.11090306174e-05
ko04725	Cholinergic synapse	27/515	160/7206	2.72132192845e-05
ko04978	Mineral absorption	11/515	40/7206	7.66945919341e-05
ko04964	Proximal tubule bicarbonate reclamation	9/515	29/7206	0.000124422543481
ko04976	Bile secretion	16/515	80/7206	0.000135983177804
ko04911	Insulin secretion	20/515	117/7206	0.000205114135224
ko04974	Protein digestion and absorption	17/515	96/7206	0.000395312360948
ko04512	ECM-receptor interaction	15/515	79/7206	0.000396915071918
ko03040	Spliceosome	1/515	145/7206	0.000461169404316
ko04977	Vitamin digestion and absorption	7/515	22/7206	0.000605142440526
ko05014	Amyotrophic lateral sclerosis (ALS)	14/515	74/7206	0.000639115249583
ko05164	Influenza A	2/515	167/7206	0.00066781449685
ko04120	Ubiquitin mediated proteolysis	1/515	138/7206	0.000668294948272
ko05150	Staphylococcus aureus infection	9/515	36/7206	0.000745347943845
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/515	59/7206	0.000786375390033
ko04140	Autophagy - animal	2/515	164/7206	0.00100328635919
ko04966	Collecting duct acid secretion	7/515	26/7206	0.00181689505049
ko04726	Serotonergic synapse	20/515	137/7206	0.00205224490863
ko04540	Gap junction	19/515	128/7206	0.00250732707822
ko04975	Fat digestion and absorption	8/515	35/7206	0.00270725369286
ko05031	Amphetamine addiction	15/515	91/7206	0.00294559496536
ko04730	Long-term depression	13/515	78/7206	0.00325716139904
ko03013	RNA transport	3/515	166/7206	0.00336713125177
ko04970	Salivary secretion	15/515	95/7206	0.00364835500306
ko04924	Renin secretion	14/515	86/7206	0.0045181038132
ko05030	Cocaine addiction	12/515	73/7206	0.00518146938362
ko04621	NOD-like receptor signaling pathway	3/515	157/7206	0.00682750215019
ko04217	Necroptosis	4/515	178/7206	0.00720365163757
ko04972	Pancreatic secretion	16/515	111/7206	0.00766609410654
ko00564	Glycerophospholipid metabolism	1/515	99/7206	0.00959610651608
ko05110	Vibrio cholerae infection	10/515	63/7206	0.0131029516726
ko04141	Protein processing in endoplasmic reticulum	5/515	184/7206	0.0132404623448
ko00770	Pantothenate and CoA biosynthesis	4/515	14/7206	0.0144979885402
ko00430	Taurine and hypotaurine metabolism	4/515	14/7206	0.0144979885402
ko00250	Alanine, aspartate and glutamate metabolism	7/515	38/7206	0.0165676969883
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/515	135/7206	0.0178884024717
ko04151	PI3K-Akt signaling pathway	40/515	390/7206	0.0195401460845
ko05166	HTLV-I infection	11/515	292/7206	0.0198146781048
ko04070	Phosphatidylinositol signaling system	2/515	112/7206	0.0241476109276
ko04630	Jak-STAT signaling pathway	3/515	132/7206	0.0250047049291
ko04260	Cardiac muscle contraction	13/515	98/7206	0.0273489178038
ko00350	Tyrosine metabolism	6/515	33/7206	0.0274010295219
ko04138	Autophagy - yeast	1/515	81/7206	0.0292595938305
ko04137	Mitophagy - animal	1/515	82/7206	0.0293416599933
ko03018	RNA degradation	1/515	84/7206	0.0299589294349
ko04914	Progesterone-mediated oocyte maturation	2/515	104/7206	0.0332070846242
ko01521	EGFR tyrosine kinase inhibitor resistance	2/515	106/7206	0.0338672786734
ko04211	Longevity regulating pathway	3/515	123/7206	0.0341563878114
ko04514	Cell adhesion molecules (CAMs)	16/515	130/7206	0.0363741568518
ko05169	Epstein-Barr virus infection	7/515	206/7206	0.037892706916
ko04742	Taste transduction	9/515	61/7206	0.0387381720965
ko04024	cAMP signaling pathway	29/515	279/7206	0.0426367204748
ko03008	Ribosome biogenesis in eukaryotes	1/515	79/7206	0.043765275802
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/515	5/7206	0.0441034244052
ko04064	NF-kappa B signaling pathway	2/515	96/7206	0.04641437708
ko04668	TNF signaling pathway	3/515	120/7206	0.0472515198577