ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	151/963	423/7206	1.00087614874e-33
ko05033	Nicotine addiction	45/963	56/7206	6.3937079984e-30
ko04724	Glutamatergic synapse	75/963	152/7206	3.04906447109e-27
ko04727	GABAergic synapse	59/963	110/7206	4.61935319592e-24
ko05032	Morphine addiction	57/963	110/7206	2.71113644951e-22
ko04713	Circadian entrainment	60/963	136/7206	6.57864103247e-19
ko04723	Retrograde endocannabinoid signaling	69/963	175/7206	2.52855137253e-18
ko04728	Dopaminergic synapse	71/963	185/7206	4.63991933614e-18
ko04721	Synaptic vesicle cycle	43/963	80/7206	6.81617199213e-18
ko04725	Cholinergic synapse	62/963	160/7206	3.83088590962e-16
ko04744	Phototransduction	26/963	36/7206	9.29126445493e-16
ko04726	Serotonergic synapse	52/963	137/7206	2.62704263324e-13
ko04024	cAMP signaling pathway	81/963	279/7206	2.14876819424e-12
ko04742	Taste transduction	30/963	61/7206	1.45639599648e-11
ko04911	Insulin secretion	43/963	117/7206	1.0858875077e-10
ko04020	Calcium signaling pathway	74/963	265/7206	1.51682534843e-10
ko04740	Olfactory transduction	33/963	80/7206	5.07520464642e-10
ko04921	Oxytocin signaling pathway	60/963	209/7206	2.9113841502e-09
ko05031	Amphetamine addiction	34/963	91/7206	6.07995052602e-09
ko03040	Spliceosome	1/963	145/7206	3.7397189102e-08
ko05203	Viral carcinogenesis	11/963	277/7206	1.83527365433e-07
ko05030	Cocaine addiction	26/963	73/7206	1.1052907514e-06
ko05164	Influenza A	4/963	167/7206	1.37572267339e-06
ko04060	Cytokine-cytokine receptor interaction	6/963	191/7206	2.28650780367e-06
ko04970	Salivary secretion	30/963	95/7206	4.19027224649e-06
ko04261	Adrenergic signaling in cardiomyocytes	51/963	205/7206	5.85136870447e-06
ko04120	Ubiquitin mediated proteolysis	3/963	138/7206	6.46871607215e-06
ko04720	Long-term potentiation	30/963	99/7206	8.50489427159e-06
ko04110	Cell cycle	4/963	145/7206	1.89110940439e-05
ko05166	HTLV-I infection	17/963	292/7206	3.18288433642e-05
ko04925	Aldosterone synthesis and secretion	30/963	105/7206	3.27556134995e-05
ko05205	Proteoglycans in cancer	15/963	271/7206	3.51642872236e-05
ko04514	Cell adhesion molecules (CAMs)	35/963	130/7206	3.64718781077e-05
ko03013	RNA transport	6/963	166/7206	3.96626385458e-05
ko04966	Collecting duct acid secretion	12/963	26/7206	4.82041375349e-05
ko05322	Systemic lupus erythematosus	5/963	151/7206	4.86023890383e-05
ko04971	Gastric acid secretion	28/963	98/7206	6.34860870469e-05
ko05162	Measles	3/963	120/7206	6.39716661795e-05
ko05169	Epstein-Barr virus infection	10/963	206/7206	6.83655851721e-05
ko04621	NOD-like receptor signaling pathway	6/963	157/7206	7.69382006632e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/963	74/7206	8.05205679601e-05
ko04972	Pancreatic secretion	30/963	111/7206	0.000106593521258
ko04964	Proximal tubule bicarbonate reclamation	12/963	29/7206	0.000176194650213
ko05168	Herpes simplex infection	9/963	182/7206	0.00024151756773
ko05161	Hepatitis B	8/963	173/7206	0.000244999732365
ko04612	Antigen processing and presentation	1/963	77/7206	0.000308785671449
ko04070	Phosphatidylinositol signaling system	29/963	112/7206	0.00035674724707
ko04976	Bile secretion	22/963	80/7206	0.000709185903636
ko04022	cGMP-PKG signaling pathway	46/963	216/7206	0.00106501074242
ko04730	Long-term depression	21/963	78/7206	0.00120463007487
ko04010	MAPK signaling pathway	63/963	321/7206	0.00135314200053
ko04260	Cardiac muscle contraction	25/963	98/7206	0.00136305118977
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/963	79/7206	0.00138445888291
ko04072	Phospholipase D signaling pathway	42/963	197/7206	0.00189984043482
ko04141	Protein processing in endoplasmic reticulum	11/963	184/7206	0.0019289786746
ko04924	Renin secretion	22/963	86/7206	0.00206791051864
ko03008	Ribosome biogenesis in eukaryotes	2/963	79/7206	0.00222568887226
ko04146	Peroxisome	3/963	89/7206	0.00255046338755
ko04510	Focal adhesion	17/963	240/7206	0.00262778230944
ko04745	Phototransduction - fly	12/963	38/7206	0.00291519835255
ko04140	Autophagy - animal	10/963	164/7206	0.00355680422248
ko04974	Protein digestion and absorption	23/963	96/7206	0.00391595338424
ko04630	Jak-STAT signaling pathway	7/963	132/7206	0.00412535400951
ko04930	Type II diabetes mellitus	15/963	54/7206	0.00418048229522
ko04064	NF-kappa B signaling pathway	4/963	96/7206	0.00579588648401
ko05145	Toxoplasmosis	7/963	126/7206	0.00763019832533
ko04978	Mineral absorption	12/963	40/7206	0.0078357306622
ko00480	Glutathione metabolism	1/963	55/7206	0.00801513528875
ko00910	Nitrogen metabolism	7/963	19/7206	0.00870797774683
ko05418	Fluid shear stress and atherosclerosis	12/963	173/7206	0.00910544867073
ko05224	Breast cancer	12/963	174/7206	0.00912817852002
ko05215	Prostate cancer	6/963	111/7206	0.0106545811091
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/963	182/7206	0.0107518193073
ko04710	Circadian rhythm	12/963	43/7206	0.0108282927811
ko04657	IL-17 signaling pathway	4/963	87/7206	0.0108327501876
ko00590	Arachidonic acid metabolism	1/963	52/7206	0.0119028091537
ko05200	Pathways in cancer	48/963	492/7206	0.0134228327759
ko04330	Notch signaling pathway	2/963	62/7206	0.0136307520127
ko04218	Cellular senescence	13/963	177/7206	0.0138068857828
ko04668	TNF signaling pathway	7/963	120/7206	0.0139320623748
ko04210	Apoptosis	13/963	180/7206	0.0140483963806
ko00310	Lysine degradation	3/963	73/7206	0.0147229358656
ko04750	Inflammatory mediator regulation of TRP channels	26/963	122/7206	0.0148034958163
ko04115	p53 signaling pathway	3/963	74/7206	0.0149023539927
ko05140	Leishmaniasis	3/963	75/7206	0.0152944877683
ko04150	mTOR signaling pathway	14/963	184/7206	0.0204927206501
ko05131	Shigellosis	4/963	82/7206	0.0210042015776
ko05110	Vibrio cholerae infection	15/963	63/7206	0.0234120891524
ko03022	Basal transcription factors	1/963	44/7206	0.0245655125338
ko05144	Malaria	1/963	45/7206	0.0250867730425
ko00071	Fatty acid degradation	1/963	45/7206	0.0250867730425
ko04540	Gap junction	26/963	128/7206	0.025292347705
ko04217	Necroptosis	14/963	178/7206	0.0257176268669
ko03420	Nucleotide excision repair	1/963	46/7206	0.0261131353664
ko05416	Viral myocarditis	2/963	55/7206	0.0279408416529
ko05321	Inflammatory bowel disease (IBD)	2/963	56/7206	0.0281853345584
ko05130	Pathogenic Escherichia coli infection	4/963	77/7206	0.0286958932594
ko04610	Complement and coagulation cascades	4/963	79/7206	0.0290236722464
ko05217	Basal cell carcinoma	3/963	68/7206	0.0295663698671
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/963	14/7206	0.02985680231
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/963	59/7206	0.0315538531925
ko04658	Th1 and Th2 cell differentiation	6/963	96/7206	0.0347420967235
ko05020	Prion diseases	1/963	40/7206	0.0361384443622
ko04550	Signaling pathways regulating pluripotency of stem cells	13/963	165/7206	0.0365969766652
ko05218	Melanoma	5/963	85/7206	0.0372538173768
ko05220	Chronic myeloid leukemia	5/963	85/7206	0.0372538173768
ko05133	Pertussis	5/963	87/7206	0.0376702933283
ko04014	Ras signaling pathway	49/963	279/7206	0.0389974196915
ko04640	Hematopoietic cell lineage	3/963	64/7206	0.0406927421089
ko00280	Valine, leucine and isoleucine degradation	2/963	54/7206	0.0413562535117
ko00512	Mucin type O-glycan biosynthesis	8/963	29/7206	0.0475772329698